{"id":"W2133782627","doi":"10.1097/mib.0000000000000366","title":"Briakinumab for Treatment of Crohnʼs Disease","year":2015,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Western University; University of Calgary","funders":"","keywords":"Tolerability; Medicine; Placebo; Discontinuation; Internal medicine; Adverse effect; Clinical endpoint; Maintenance therapy; Regimen; Gastroenterology; Nausea; Crohn's disease; Clinical trial; Surgery; Chemotherapy; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153336,0.0003991385,0.001198016,0.0003520043,0.0002569515,0.0003900394,0.0003218527,0.0006070464,0.004082868],"category_scores_gemma":[0.0008500245,0.0001730398,0.0004872936,0.0003573598,0.0002900585,0.0003391076,0.0002517233,0.00133025,0.0008441681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002752925,"about_ca_system_score_gemma":0.000385331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001647576,"about_ca_topic_score_gemma":0.0005025875,"domain_scores_codex":[0.9996295,0.0001697842,0.00004470721,0.00004053763,0.00006778805,0.00004769549],"domain_scores_gemma":[0.999529,0.0001432463,0.0001604565,0.00002321481,0.00003405873,0.0001100126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.173376,0.009018898,0.01296883,0.009771797,0.001284565,0.002020413,0.0003184891,0.0005909175,0.06873178,0.0004868089,0.00498173,0.7164496],"study_design_scores_gemma":[0.384001,0.4248655,0.08322635,0.00151934,0.002463731,0.008840312,0.0001700897,0.0008062865,0.01634706,0.0006690567,0.07702029,0.00007099053],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7916614,0.1972488,0.0007924541,0.002223818,0.0008541702,0.001237157,0.0003226119,0.0001330991,0.005526423],"genre_scores_gemma":[0.953624,0.03852957,0.001605245,0.002006512,0.0008691655,0.0005862032,0.0004028504,0.00001472104,0.002361753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004082868,"threshold_uncertainty_score":0.01365852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741402943808773,"score_gpt":0.2641439551631881,"score_spread":0.2467299257251004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}