{"id":"W2133936786","doi":"10.1086/605847","title":"Dengue Virus NS5 Inhibits Interferon‐α Signaling by Blocking Signal Transducer and Activator of Transcription 2 Phosphorylation","year":2009,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"STAT2; Dengue virus; STAT protein; Interferon; Signal transduction; Biology; STAT1; Flavivirus; Phosphorylation; Activator (genetics); Mediator; Virology; Dengue fever; Cell biology; Virus; Receptor; STAT3; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002423022,0.0001406971,0.0003339564,0.0001351958,0.00006106107,0.00001891058,0.00006092342,0.00005111332,0.00008984492],"category_scores_gemma":[0.00005035665,0.00009785339,0.0001643269,0.0001520046,0.00004911884,0.0001888732,0.000004127797,0.000203782,4.339698e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006395399,"about_ca_system_score_gemma":0.00008306353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000448704,"about_ca_topic_score_gemma":0.000008869293,"domain_scores_codex":[0.9989034,0.0001081427,0.0004742517,0.00009682379,0.0002626308,0.0001547425],"domain_scores_gemma":[0.9992465,0.0001037055,0.0002752471,0.00008969038,0.0001401377,0.0001447166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003400969,0.0008402317,0.01853081,0.0000876024,0.0001487833,0.00001590449,0.001000801,0.0004956369,0.9464342,0.00002682679,0.0001479935,0.02887023],"study_design_scores_gemma":[0.01910592,0.007198876,0.3044305,0.00252164,0.004079246,0.0005033411,0.001626312,0.002054261,0.6557753,0.001921366,0.0002318433,0.0005513645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893609,0.008654753,0.001322941,0.0003166265,0.00006025591,0.0002133251,0.00001651612,0.00001270723,0.0000420033],"genre_scores_gemma":[0.9990405,0.0005176351,0.000006051192,0.0002649063,0.0001461048,0.000002084182,0.000003485187,0.00001218694,0.000007006171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2906589,"threshold_uncertainty_score":0.3990345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006209049156980708,"score_gpt":0.2349109027214908,"score_spread":0.2287018535645101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}