{"id":"W2133961060","doi":"10.1097/aln.0b013e3181d7b13a","title":"Phase II Study to Evaluate the Safety and Efficacy of the Oral Neurokinin-1 Receptor Antagonist Casopitant (GW679769) Administered with Ondansetron for the Prevention of Postoperative and Postdischarge Nausea and Vomiting in High-risk Patients","year":2010,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Toronto Western Hospital; University Health Network","funders":"","keywords":"Ondansetron; Medicine; Retching; Vomiting; Anesthesia; Antiemetic; Nausea; Postoperative nausea and vomiting; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002488534,0.001701602,0.002852481,0.0004916398,0.000502898,0.001010813,0.001239978,0.002080792,0.006430025],"category_scores_gemma":[0.002293081,0.0008600008,0.001366543,0.0004917094,0.00149953,0.001062101,0.000389599,0.004007474,0.001174343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009929447,"about_ca_system_score_gemma":0.00287006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009637755,"about_ca_topic_score_gemma":0.001893729,"domain_scores_codex":[0.9991521,0.0004464354,0.0000475206,0.0001326744,0.00008411858,0.0001372235],"domain_scores_gemma":[0.9977311,0.0004409666,0.0004984796,0.0002101996,0.0001571478,0.0009621746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8866868,0.07310116,0.003429692,0.0003026342,0.0009884416,0.0001247905,0.00008918811,0.0005331268,0.01397846,0.0001437749,0.001253223,0.01936869],"study_design_scores_gemma":[0.6674395,0.3265859,0.003478933,0.00001383054,0.000295266,0.00009625583,0.00002175456,0.0003687707,0.0009632985,0.00008394366,0.0006420768,0.00001037732],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882184,0.001388898,0.0009238333,0.0004688254,0.0002755873,0.005922011,0.001257838,0.00008055178,0.001464137],"genre_scores_gemma":[0.9804053,0.001390631,0.002944437,0.001369267,0.0005743677,0.008450513,0.002213349,0.00003156616,0.0026207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006430025,"threshold_uncertainty_score":0.0215106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01849574452264644,"score_gpt":0.3133198305478317,"score_spread":0.2948240860251852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}