{"id":"W2133961060","doi":"10.1097/aln.0b013e3181d7b13a","title":"Phase II Study to Evaluate the Safety and Efficacy of the Oral Neurokinin-1 Receptor Antagonist Casopitant (GW679769) Administered with Ondansetron for the Prevention of Postoperative and Postdischarge Nausea and Vomiting in High-risk Patients","year":2010,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Toronto Western Hospital; University Health Network","funders":"","keywords":"Ondansetron; Medicine; Retching; Vomiting; Anesthesia; Antiemetic; Nausea; Postoperative nausea and vomiting; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008509179,0.0001426084,0.0003279904,0.00005009427,0.0002708468,0.00001070712,0.0001006861,0.00004062638,0.000004804509],"category_scores_gemma":[0.0004190167,0.00006415963,0.00002808776,0.000105297,0.0002401285,0.00003209907,0.0001167261,0.0001890482,1.78923e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009074933,"about_ca_system_score_gemma":0.00004270463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001669545,"about_ca_topic_score_gemma":0.000402611,"domain_scores_codex":[0.9987698,0.0003354326,0.0003316227,0.0002675778,0.0001275415,0.0001680524],"domain_scores_gemma":[0.9988411,0.0005516946,0.0001834047,0.00027715,0.0001034822,0.00004316789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01081273,0.001706813,0.9589775,0.00004702143,0.0001320043,0.00000434388,0.006601891,0.000002079267,0.00720934,0.0003721919,0.00003275043,0.01410131],"study_design_scores_gemma":[0.01368532,0.02669896,0.9561964,0.00005563303,0.0002656198,0.00001435043,0.001309314,0.0000565439,0.001313232,0.00001960284,0.0003101308,0.00007489303],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951568,0.00003837558,0.000004438115,0.001787042,0.0000675394,0.002902274,0.00003188778,0.000005139795,0.000006451089],"genre_scores_gemma":[0.9994425,0.00002992909,0.0001293882,0.0002660479,0.00001935911,0.00004520033,0.00001149224,0.00001430573,0.00004177185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02499215,"threshold_uncertainty_score":0.2616354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01849574452264644,"score_gpt":0.3133198305478317,"score_spread":0.2948240860251852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}