{"id":"W2133973959","doi":"10.1128/mbio.01183-14","title":"Antivirulence Activity of the Human Gut Metabolome","year":2014,"lang":"en","type":"article","venue":"mBio","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"University of British Columbia; Ciência sem Fronteiras; Foreign Affairs and International Trade Canada; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Biology; Metabolome; Virulence; Function (biology); Clostridia; Gut flora; Host (biology); Human health; Computational biology; Human pathogen; Microbiology; Bacteria; Genetics; Gene; Metabolomics; Bioinformatics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001363796,0.00005877901,0.00008538362,0.000009050632,0.00007229818,0.000004206139,0.000163582,0.00006398492,0.00001268418],"category_scores_gemma":[0.00002276037,0.00004134753,0.0000576718,0.00004086576,0.00007717751,0.000001126124,0.00008694348,0.00005313564,0.000007156844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002910283,"about_ca_system_score_gemma":0.000022636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005584249,"about_ca_topic_score_gemma":0.00004478861,"domain_scores_codex":[0.9995661,0.00006196718,0.00007389046,0.0001357274,0.00004474828,0.0001175979],"domain_scores_gemma":[0.9995766,0.000003739109,0.00005975846,0.0003145139,0.00002402203,0.00002136122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003811091,0.00002755303,0.007478253,0.00001282146,0.000006585528,3.121329e-8,0.00001234242,4.864279e-7,0.9906633,0.0003067938,0.0006957495,0.0007922444],"study_design_scores_gemma":[0.0001161106,0.00004510738,0.2583193,0.000004694317,0.000005588547,0.000001198023,0.000002425907,0.000002235389,0.7130862,0.00005392661,0.02831692,0.00004624131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973207,0.00009716635,0.0001646629,0.0001693327,0.00009378696,0.0000656606,0.000008501238,0.000003519949,0.002076662],"genre_scores_gemma":[0.9988759,0.00001475063,0.00006805467,0.0001937106,0.00006965339,0.000001701575,0.000004533628,0.000005620283,0.0007660661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2775771,"threshold_uncertainty_score":0.1686103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00956397243056169,"score_gpt":0.2612592925988345,"score_spread":0.2516953201682728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}