{"id":"W2133973959","doi":"10.1128/mbio.01183-14","title":"Antivirulence Activity of the Human Gut Metabolome","year":2014,"lang":"en","type":"article","venue":"mBio","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"University of British Columbia; Ciência sem Fronteiras; Foreign Affairs and International Trade Canada; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Biology; Metabolome; Virulence; Function (biology); Clostridia; Gut flora; Host (biology); Human health; Computational biology; Human pathogen; Microbiology; Bacteria; Genetics; Gene; Metabolomics; Bioinformatics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009078118,0.0002465937,0.0001491596,0.0003633818,0.000109929,0.0002692206,0.00004605716,0.0001408636,0.002959671],"category_scores_gemma":[0.0001777445,0.00006100699,0.0001356167,0.0001307285,0.00009569091,0.00007304209,0.0001646371,0.0002502731,0.0005272555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001228981,"about_ca_system_score_gemma":0.0001336058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008207521,"about_ca_topic_score_gemma":0.0008063721,"domain_scores_codex":[0.9999589,0.000009487262,0.000001534493,0.00001101161,0.000008386792,0.00001068549],"domain_scores_gemma":[0.9999588,0.00000769293,0.000007390145,0.000003482375,0.000008345366,0.00001432568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002789387,0.00008418923,0.01500083,0.0001756933,0.00007402338,0.0003535835,0.0000562325,0.0001136799,0.927947,0.0003779673,0.001147188,0.05188019],"study_design_scores_gemma":[0.0001849727,0.002009899,0.4666792,0.0001343585,0.0002298872,0.002512082,0.0002861609,0.001554738,0.4696352,0.0009952869,0.0557402,0.00003798306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9504069,0.03326718,0.001401787,0.0009809695,0.0001499898,0.00004240615,0.002298145,0.0001604375,0.01129207],"genre_scores_gemma":[0.9879936,0.004970499,0.0008649051,0.0002897964,0.00007049197,0.00001811368,0.001622703,0.00001880687,0.004151085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002959671,"threshold_uncertainty_score":0.009901106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00956397243056169,"score_gpt":0.2612592925988345,"score_spread":0.2516953201682728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}