{"id":"W2133980028","doi":"10.1139/w05-122","title":"Bioreactor studies on the endophytic fungus <i>Entrophospora infrequens</i> for the production of an anticancer alkaloid camptothecin","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Camptothecin; Alkaloid; Bark (sound); Fungus; Plant use of endophytic fungi in defense; Botany; Traditional medicine; Chemistry; Biology; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777373,0.0003672286,0.0004346751,0.0001658666,0.0002299349,0.0003118993,0.0002426066,0.0002666004,0.0005657206],"category_scores_gemma":[0.0001869288,0.0001189002,0.0003135773,0.0002097927,0.00009593302,0.0002511681,0.0002458085,0.0004194899,0.0003410633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002442487,"about_ca_system_score_gemma":0.0002235885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003220025,"about_ca_topic_score_gemma":0.003903429,"domain_scores_codex":[0.999838,0.00002855511,0.00001844652,0.00003374158,0.00005074267,0.00003046435],"domain_scores_gemma":[0.9998311,0.00005464959,0.00003374856,0.0000184833,0.00003573861,0.00002627358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000441494,0.00003011672,0.0001671358,0.00001994548,0.000002222584,0.00004693265,0.0000138234,0.00002856486,0.9990993,0.000008947862,0.000008161274,0.0005306745],"study_design_scores_gemma":[0.00001146122,0.0006417966,0.007863606,0.000005477432,0.00001858086,0.00024891,0.00006983572,0.0004800238,0.9900512,0.00001252191,0.0005915003,0.000005165454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977901,0.0004102456,0.0007943839,0.00004047156,0.00001245526,0.0000344607,0.0001703252,0.00002148849,0.0007260734],"genre_scores_gemma":[0.9938623,0.0006144,0.003161658,0.00003604844,0.000009699595,0.00003693721,0.0005737555,0.00001307007,0.001692171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003220025,"threshold_uncertainty_score":0.006402552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02039853133018065,"score_gpt":0.2453924837000174,"score_spread":0.2249939523698367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}