{"id":"W2133980496","doi":"10.1177/1479164115570301","title":"Design and baseline characteristics of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA <sup>®</sup> )","year":2015,"lang":"en","type":"article","venue":"Diabetes and Vascular Disease Research","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":206,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Eli Lilly and Company","keywords":"Glimepiride; Medicine; Linagliptin; Type 2 diabetes; Internal medicine; Hazard ratio; Diabetes mellitus; Myocardial infarction; Regimen; Metformin; Randomized controlled trial; Confidence interval; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004401954,0.001567441,0.001682905,0.0008690701,0.001133522,0.001242157,0.001063086,0.001655102,0.02239054],"category_scores_gemma":[0.007029301,0.0006636082,0.000986863,0.001373675,0.0007319399,0.0009442173,0.0005598197,0.001821327,0.005351522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108437,"about_ca_system_score_gemma":0.002573895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001631727,"about_ca_topic_score_gemma":0.002041953,"domain_scores_codex":[0.9961384,0.001569057,0.0003391209,0.000916628,0.0005089278,0.0005278619],"domain_scores_gemma":[0.9973749,0.0004981683,0.000672907,0.000253036,0.0004752626,0.0007257062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5319777,0.0167498,0.3213897,0.002102923,0.002277341,0.0007518714,0.0006398607,0.001718019,0.003576253,0.003248467,0.03962017,0.07594789],"study_design_scores_gemma":[0.1409588,0.1375688,0.6145805,0.0008836661,0.003030287,0.001572936,0.0007412345,0.003665434,0.001940118,0.009550791,0.08507569,0.0004316929],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.7395334,0.01279718,0.01277697,0.004770443,0.001619359,0.09213634,0.09730668,0.0002178783,0.03884174],"genre_scores_gemma":[0.7712723,0.002427115,0.01066271,0.006002648,0.0009020598,0.1477817,0.03393466,0.000115667,0.02690119],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.02239054,"threshold_uncertainty_score":0.07490385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09392858695292594,"score_gpt":0.333408670727387,"score_spread":0.2394800837744611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}