{"id":"W2134079336","doi":"10.1126/scitranslmed.3004190","title":"Optogenetic and Potassium Channel Gene Therapy in a Rodent Model of Focal Neocortical Epilepsy","year":2012,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":276,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Action Medical Research; Wellcome Trust","keywords":"Optogenetics; Epilepsy; Neuroscience; Medicine; Electroencephalography; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009209704,0.0001158098,0.0001815063,0.0003191768,0.00009933013,0.000009908368,0.0003017786,0.00003689166,0.00007902403],"category_scores_gemma":[0.0002201748,0.00008745334,0.00002412064,0.0007573313,0.001791643,0.0002081092,0.00003461233,0.0001416798,0.00000324191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002442575,"about_ca_system_score_gemma":0.0001793759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002672847,"about_ca_topic_score_gemma":0.000004999769,"domain_scores_codex":[0.9976634,0.00006072215,0.0002967255,0.0003341674,0.001154686,0.0004903157],"domain_scores_gemma":[0.9992565,0.0001808073,0.00003842737,0.0001578438,0.00006398319,0.0003024233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007019794,0.0001105233,0.01731864,0.000006786305,7.00611e-7,6.906122e-7,0.001378129,0.001422209,0.9745359,0.002008872,0.00000270632,0.003144671],"study_design_scores_gemma":[0.001135343,0.000230668,0.1382665,0.00002498027,0.000003594023,0.00001464181,0.00004344152,0.1794623,0.6774566,0.003223683,0.00001642929,0.0001218281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929004,0.0005772748,0.00401888,0.001255108,0.0001550625,0.0002983467,0.00001274537,0.000008551037,0.0007736238],"genre_scores_gemma":[0.9984741,0.0003619418,0.0008075029,0.0002133005,0.00009440746,0.00002279155,0.000001378431,0.000008089176,0.00001648359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2970792,"threshold_uncertainty_score":0.6601385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.112445376932379,"score_gpt":0.3629004956065752,"score_spread":0.2504551186741963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}