{"id":"W2134108900","doi":"10.1016/j.atherosclerosis.2010.08.010","title":"Response of the endothelial cell transcriptome to supraphysiological laminar shear stress","year":2010,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Laminar flow; Shear stress; Shear (geology); Transcriptome; Stress (linguistics); Materials science; Cell biology; Chemistry; Biology; Composite material; Mechanics; Gene expression; Biochemistry; Physics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001950188,0.0001308482,0.0001362032,0.00001831293,0.00007867051,0.0000100446,0.0003659094,0.0001574558,0.00009143064],"category_scores_gemma":[0.00004098513,0.00008762893,0.0002273177,0.0001072428,0.0001294307,0.000002045885,0.00008644599,0.00008785167,0.00001139052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004351897,"about_ca_system_score_gemma":0.00003735524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002679384,"about_ca_topic_score_gemma":0.00001971508,"domain_scores_codex":[0.9991434,0.00009504172,0.0001586357,0.0002680391,0.0001297184,0.0002051646],"domain_scores_gemma":[0.9993276,0.00002155218,0.00005142317,0.0004792993,0.00005130306,0.00006880223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003150785,0.00008952826,0.0100826,0.000005412468,0.00001237719,7.882777e-8,0.0001195415,0.00001608157,0.98814,0.00002554497,0.0009858953,0.0002078135],"study_design_scores_gemma":[0.0002477171,0.0002745466,0.1629857,0.00000804906,0.00001007405,6.598633e-7,0.00005025576,0.00000152625,0.8177998,0.000005602304,0.01851533,0.0001006903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987554,0.00006269995,0.000119357,0.0002683108,0.0002969518,0.000164651,0.0001867363,0.000007779995,0.0001380892],"genre_scores_gemma":[0.9981458,0.00004920975,0.0005174757,0.0005459059,0.0001453485,0.00003312381,0.000005287759,0.0000219102,0.0005359282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1703402,"threshold_uncertainty_score":0.3573404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0121714878455673,"score_gpt":0.2369276877430089,"score_spread":0.2247561998974416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}