{"id":"W2134123786","doi":"10.1093/cercor/bht237","title":"Rescue of NMDAR-Dependent Synaptic Plasticity in Fmr1 Knock-Out Mice","year":2013,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Canadian Institutes of Health Research","keywords":"FMR1; Fragile X syndrome; NMDA receptor; Synaptic plasticity; Neuroscience; Metaplasticity; Dentate gyrus; Neuroplasticity; Knockout mouse; Biology; Nonsynaptic plasticity; Hippocampus; Psychology; Receptor; Fragile x; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003047597,0.001364797,0.0007654812,0.001018328,0.0004080854,0.0003844057,0.0008111259,0.001037467,0.003226507],"category_scores_gemma":[0.000210397,0.0004611986,0.0006724211,0.0002534948,0.0005753497,0.0003381546,0.0004814248,0.001457293,0.001152894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000592237,"about_ca_system_score_gemma":0.0004057517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00156594,"about_ca_topic_score_gemma":0.002304696,"domain_scores_codex":[0.9996686,0.00003315309,0.00006207035,0.0001061142,0.00007641294,0.00005366978],"domain_scores_gemma":[0.9995988,0.00004224401,0.0001577609,0.0000342952,0.00003243381,0.0001344938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008296829,0.00004122698,0.00007466067,0.00006346692,0.00001132656,0.0001805453,0.00002606442,0.00008881932,0.9981857,0.0001710818,0.0000773407,0.0009969369],"study_design_scores_gemma":[0.0001066593,0.0004874204,0.00310104,0.00005472386,0.00004753168,0.0008788872,0.00005116879,0.001292827,0.9904613,0.0001469253,0.003355343,0.00001617875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757804,0.002408162,0.0123462,0.0005176928,0.0001912392,0.0002266862,0.004752973,0.0011467,0.002629915],"genre_scores_gemma":[0.9610637,0.003661509,0.01699392,0.0002368198,0.00004541613,0.0004977886,0.003310754,0.0003257271,0.01386436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003226507,"threshold_uncertainty_score":0.01079381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00899658558878918,"score_gpt":0.2197719087680611,"score_spread":0.2107753231792719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}