{"id":"W2134155449","doi":"10.1093/intimm/dxv016","title":"<i>Enterococcus faecalis</i>lipoteichoic acid suppresses<i>Aggregatibacter actinomycetemcomitans</i>lipopolysaccharide-induced IL-8 expression in human periodontal ligament cells","year":2015,"lang":"en","type":"article","venue":"International Immunology","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"Korea Health Industry Development Institute; National Research Foundation of Korea; Ministry of Agriculture, Food and Rural Affairs; National Research Foundation","keywords":"Lipoteichoic acid; Aggregatibacter actinomycetemcomitans; Lipopolysaccharide; Molecular biology; Chemistry; Microbiology; Protein kinase A; Small interfering RNA; Virulence factor; p38 mitogen-activated protein kinases; Kinase; Chemokine; Biology; Cell biology; Receptor; Porphyromonas gingivalis; Immunology; Virulence; Biochemistry; Transfection; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004044327,0.0003857383,0.0005299059,0.0004494542,0.000153037,0.0001979402,0.001231334,0.0005118488,0.001993159],"category_scores_gemma":[0.0001455432,0.000376884,0.0001968384,0.0001365855,0.0002445898,0.0005991186,0.0007088527,0.0009883329,0.001153946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004853509,"about_ca_system_score_gemma":0.0001123423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001214824,"about_ca_topic_score_gemma":0.001149408,"domain_scores_codex":[0.9969726,0.0004222293,0.0008099441,0.0007187139,0.0003769966,0.0006995664],"domain_scores_gemma":[0.9986225,0.0001037896,0.0002714568,0.0005648989,0.0002756164,0.0001617089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000456156,0.000322726,0.02535202,0.00001050627,0.0001438131,0.0003812582,0.0005289075,0.00000572453,0.9694256,0.000114724,0.002192305,0.001066243],"study_design_scores_gemma":[0.00304462,0.0002621716,0.01705768,0.000138035,0.0000112855,0.0003594264,0.0004553582,0.00001744764,0.9518177,0.0001714704,0.02628778,0.0003770328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905962,0.0004911601,0.00006181317,0.0005742306,0.004996408,0.0003794991,0.0001932345,0.00009913855,0.002608356],"genre_scores_gemma":[0.9962653,0.00005187354,0.0001745679,0.0002611674,0.0003428083,0.0001186842,0.0002458936,0.00004811965,0.002491564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02409548,"threshold_uncertainty_score":0.9998683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03377148352340226,"score_gpt":0.313629884608359,"score_spread":0.2798584010849567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}