{"id":"W2134161293","doi":"10.1136/bjophthalmol-2014-305327","title":"Multi-country real-life experience of anti-vascular endothelial growth factor therapy for wet age-related macular degeneration","year":2014,"lang":"en","type":"article","venue":"British Journal of Ophthalmology","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":613,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Allergan; Genentech; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology; Carl Zeiss Meditec AG; National Institute for Health and Care Research; Heidelberg Engineering; Bayer HealthCare; Alimera Sciences; Servier; Pfizer","keywords":"Medicine; Visual acuity; Ranibizumab; Macular degeneration; Ophthalmology; Observational study; Retrospective cohort study; Clinical trial; Surgery; Bevacizumab; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001642653,0.000131109,0.0003625572,0.0004936257,0.0005291337,0.0008489774,0.0002560411,0.0003881273,0.001177798],"category_scores_gemma":[0.003954919,0.0001594676,0.0004082731,0.0008572715,0.000469668,0.0004889654,0.0005587472,0.0004910004,0.0001746844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008567,"about_ca_system_score_gemma":0.0007790939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008823778,"about_ca_topic_score_gemma":0.01314403,"domain_scores_codex":[0.9982622,0.0008933164,0.000201937,0.0002046044,0.0002342579,0.0002036284],"domain_scores_gemma":[0.9930198,0.0009561171,0.004844703,0.0001846915,0.0003444882,0.0006501822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003973835,0.0001813868,0.9954231,0.0000496162,0.0001205674,0.0001661013,0.0002991601,0.00009990464,0.0001083744,0.00001215616,0.0001463654,0.002995896],"study_design_scores_gemma":[0.00006008395,0.0007935675,0.9964215,0.00003926589,0.00006610099,0.001123586,0.0005053341,0.0001382657,0.0001038377,0.00001389489,0.0007213507,0.0000134093],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986884,0.0005321704,0.00004566022,0.0000664879,0.00000308311,0.00001447779,0.0003245364,0.0000016539,0.0003234253],"genre_scores_gemma":[0.9993949,0.0002195954,0.00007252185,0.00004479538,0.000006888481,0.00001346431,0.0001970831,8.034061e-7,0.00004994027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008823778,"threshold_uncertainty_score":0.01754487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02631865879130767,"score_gpt":0.3086095319800354,"score_spread":0.2822908731887278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}