{"id":"W2134174762","doi":"10.1128/aem.00413-10","title":"Novel, Versatile, and Tightly Regulated Expression System for <i>E</i> <i>scherichia coli</i> Strains","year":2010,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Biotechnology Research Institute; McGill University","funders":"","keywords":"lac operon; Lac repressor; Inducer; Repressor; Operon; Pseudomonas putida; Escherichia coli; Population; Biology; Gene expression; Gene; Molecular biology; Regulation of gene expression; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002354167,0.0007415536,0.0005995596,0.0003541815,0.0002100987,0.000560368,0.0005959935,0.0004144475,0.0005229645],"category_scores_gemma":[0.0002365987,0.0002350542,0.0004128605,0.0003801753,0.0002409285,0.0003284058,0.0005263762,0.001086602,0.0006665628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005113771,"about_ca_system_score_gemma":0.0003571735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009667714,"about_ca_topic_score_gemma":0.0009555985,"domain_scores_codex":[0.9996502,0.00005011211,0.00004317001,0.0000933451,0.0001041236,0.00005898796],"domain_scores_gemma":[0.9998478,0.00002275367,0.00004188885,0.00002380822,0.00003420718,0.00002956716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002110487,0.00001100937,0.00005315182,0.00001506603,0.00000167802,0.00001760195,0.000007625356,0.00005335064,0.9985986,0.00008704017,0.00003943077,0.001094351],"study_design_scores_gemma":[0.000007138159,0.00005360347,0.0005842875,0.000003132433,0.000007637602,0.000108192,0.00001028532,0.0008761942,0.9955183,0.00002797033,0.002794087,0.000009217179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7942843,0.001356695,0.1954468,0.0003745978,0.0001572198,0.0003925065,0.002742026,0.002029157,0.003216661],"genre_scores_gemma":[0.80056,0.001483441,0.1815026,0.0002206003,0.0000600032,0.0005156533,0.007110314,0.0006106404,0.007936688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009667714,"threshold_uncertainty_score":0.00371033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002894340759577461,"score_gpt":0.1631616229085277,"score_spread":0.1602672821489503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}