{"id":"W2134188737","doi":"10.1128/jvi.79.16.10750-10763.2005","title":"Myxoma Virus M-T5 Protects Infected Cells from the Stress of Cell Cycle Arrest through Its Interaction with Host Cell Cullin-1","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Muscular Dystrophy Canada; Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cullin; Cell cycle; Cell biology; Cell cycle checkpoint; Myxoma virus; G1 phase; Ankyrin repeat; Cell; Molecular biology; Ubiquitin; Virus; Virology; Ubiquitin ligase; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002516808,0.000191606,0.0002781673,0.0000579771,0.00007370575,0.00002045283,0.0004230625,0.0002073186,0.0001400137],"category_scores_gemma":[0.00003472642,0.0001282435,0.0001264696,0.000115139,0.0001425941,0.00002004423,0.00008428148,0.000483099,0.00002518732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002926989,"about_ca_system_score_gemma":0.0001667034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006013714,"about_ca_topic_score_gemma":0.0005800432,"domain_scores_codex":[0.9984514,0.0003436279,0.0004335548,0.0002249854,0.0002577202,0.0002887004],"domain_scores_gemma":[0.9986194,0.00009110604,0.0005942071,0.0003491609,0.0002660546,0.00008002951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005099263,0.000431968,0.0003842062,0.00001489863,0.0001143278,0.00001677462,0.0002090915,0.003663308,0.9892632,8.613908e-7,0.0004987638,0.0003033363],"study_design_scores_gemma":[0.001805057,0.006460958,0.001543066,0.00002461485,0.00003677089,0.00002349355,0.00008276889,0.000119847,0.9842985,0.00001503987,0.005461128,0.000128738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969144,0.001342648,0.0003800191,0.0005539301,0.0001796725,0.0002641846,0.00005337385,0.000004308532,0.0003074311],"genre_scores_gemma":[0.997529,0.0008559701,0.0003961535,0.00038959,0.0006852003,0.000008396985,0.00001521439,0.00003236623,0.00008805171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00602899,"threshold_uncertainty_score":0.522962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105537255244482,"score_gpt":0.2733872092060987,"score_spread":0.2623318366536539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}