{"id":"W2134188737","doi":"10.1128/jvi.79.16.10750-10763.2005","title":"Myxoma Virus M-T5 Protects Infected Cells from the Stress of Cell Cycle Arrest through Its Interaction with Host Cell Cullin-1","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Muscular Dystrophy Canada; Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cullin; Cell cycle; Cell biology; Cell cycle checkpoint; Myxoma virus; G1 phase; Ankyrin repeat; Cell; Molecular biology; Ubiquitin; Virus; Virology; Ubiquitin ligase; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007571666,0.0002057032,0.0001654247,0.0001034862,0.0001336305,0.0002339493,0.0001561283,0.0001589696,0.0006760001],"category_scores_gemma":[0.00007831472,0.00009343524,0.0001662671,0.00006706832,0.0001080543,0.0001334746,0.0001478254,0.0003015636,0.0001421472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002418103,"about_ca_system_score_gemma":0.0001608339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007272651,"about_ca_topic_score_gemma":0.0008712,"domain_scores_codex":[0.9999341,0.00001110633,0.000007528382,0.00001347173,0.00001135809,0.00002251232],"domain_scores_gemma":[0.9999512,0.000007285216,0.00001581312,0.000008158153,0.000004186158,0.00001326459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001071416,0.00001702179,0.0002795607,0.00002133501,0.00000384008,0.00001981126,0.000009746579,0.00002581494,0.9989173,0.00004910982,0.00001462913,0.0005346726],"study_design_scores_gemma":[0.00001643378,0.0004061245,0.012439,0.00001111485,0.00001105966,0.0001761558,0.00003285503,0.0006880674,0.9848971,0.00002997262,0.001289165,0.000002984712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981847,0.0008670748,0.0003904969,0.00002123106,0.00000693221,0.000007639691,0.0000917653,0.00001664542,0.0004134635],"genre_scores_gemma":[0.9983829,0.0002757141,0.0003694564,0.00001248371,0.000003361733,0.000009010621,0.0002049891,0.000003690173,0.0007383726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007272651,"threshold_uncertainty_score":0.00226146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105537255244482,"score_gpt":0.2733872092060987,"score_spread":0.2623318366536539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}