{"id":"W2134191440","doi":"10.1371/journal.pone.0054846","title":"The Immediately Releasable Pool of Mouse Chromaffin Cell Vesicles Is Coupled to P/Q-Type Calcium Channels via the Synaptic Protein Interaction Site","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Secretaría de Ciencia y Técnica, Universidad de Buenos Aires; Universidad de Buenos Aires; Alberta Heritage Foundation for Medical Research; Consejo Nacional de Investigaciones Científicas y Técnicas; Fondation pour la Recherche Médicale","keywords":"Exocytosis; Synaptic vesicle; Biophysics; Vesicle; Voltage-dependent calcium channel; Coupling (piping); Membrane potential; Chromaffin cell; Cell biology; Calcium; Biology; Chemistry; Secretion; Neuroscience; Membrane; Biochemistry; Materials science; Adrenal medulla","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352336,0.0002753581,0.0003112366,0.0001351422,0.0001203092,0.0004178689,0.0003317521,0.0002533913,0.0006208455],"category_scores_gemma":[0.0001184759,0.0001695494,0.0003712522,0.0001331554,0.0001857043,0.0003160772,0.0002725132,0.0004816539,0.0002634623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003307535,"about_ca_system_score_gemma":0.0001704284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006043303,"about_ca_topic_score_gemma":0.0007104554,"domain_scores_codex":[0.9998099,0.00002071424,0.00001528934,0.00005719193,0.00004555661,0.00005142375],"domain_scores_gemma":[0.9998971,0.00001428579,0.00003130339,0.00001544201,0.00001042269,0.00003138985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002669951,0.000004455414,0.00005711524,0.000008999205,0.000002311989,0.00002859655,0.00000362329,0.00001235385,0.9996506,0.00004599534,0.000003435733,0.0001557756],"study_design_scores_gemma":[0.00001806755,0.0002116439,0.008597787,0.000005021189,0.00002587808,0.0002941876,0.00001535559,0.0006778495,0.988647,0.00004614837,0.001456418,0.000004505423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943954,0.001176735,0.003598608,0.00004370833,0.00001428044,0.00002605869,0.0001453417,0.00004315435,0.0005567403],"genre_scores_gemma":[0.9948893,0.0006641122,0.002539284,0.00003944607,0.00001160659,0.00003301373,0.0003749083,0.00002085019,0.00142742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006208455,"threshold_uncertainty_score":0.002399743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859454245840069,"score_gpt":0.2085823332474838,"score_spread":0.1899877907890831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}