{"id":"W2134216504","doi":"10.1110/ps.0303603","title":"Interaction of the 18.5‐kD isoform of myelin basic protein with Ca<sup>2+</sup>‐calmodulin: Effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism","year":2003,"lang":"en","type":"article","venue":"Protein Science","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Chemistry; Citrullination; Myelin basic protein; Circular dichroism; Dissociation constant; Calmodulin; Dynamic light scattering; Fluorescence spectroscopy; Protein secondary structure; Conformational change; Crystallography; Fluorescence; Biophysics; Stereochemistry; Biochemistry; Arginine; Enzyme; Myelin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001406237,0.0002211875,0.0001734561,0.00005138789,0.00008783497,0.0001471474,0.0002321293,0.0002232599,0.0005343425],"category_scores_gemma":[0.0003462226,0.00008701058,0.0001020401,0.00008924102,0.0001260588,0.00009958653,0.0001151952,0.0002407239,0.000155976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001925219,"about_ca_system_score_gemma":0.00008146127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008916198,"about_ca_topic_score_gemma":0.001092759,"domain_scores_codex":[0.9998686,0.00002780482,0.000008426962,0.00002776831,0.00003829005,0.00002904931],"domain_scores_gemma":[0.9998215,0.00006640584,0.00004027553,0.00001099443,0.00002628157,0.00003447726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001605464,0.0000156789,0.000265374,0.00001927314,0.000005413846,0.00002477735,0.00001085336,0.00003295257,0.9990067,0.000009428381,0.00001228713,0.0004367371],"study_design_scores_gemma":[0.00001713516,0.0003352334,0.008363287,0.000003157021,0.000009741294,0.0002267472,0.00001420461,0.001072467,0.9887988,0.00001239749,0.001142515,0.000004410967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989105,0.000483171,0.000358456,0.00001961191,0.000003674195,0.00000542413,0.00004047217,0.000004594895,0.0001740754],"genre_scores_gemma":[0.9970681,0.0003386769,0.001648216,0.00003582775,0.000006511721,0.00001359927,0.0003007088,0.0000097938,0.0005785109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008916198,"threshold_uncertainty_score":0.001787603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004884844783018555,"score_gpt":0.2519024845294764,"score_spread":0.2470176397464579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}