{"id":"W2134216504","doi":"10.1110/ps.0303603","title":"Interaction of the 18.5‐kD isoform of myelin basic protein with Ca<sup>2+</sup>‐calmodulin: Effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism","year":2003,"lang":"en","type":"article","venue":"Protein Science","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Chemistry; Citrullination; Myelin basic protein; Circular dichroism; Dissociation constant; Calmodulin; Dynamic light scattering; Fluorescence spectroscopy; Protein secondary structure; Conformational change; Crystallography; Fluorescence; Biophysics; Stereochemistry; Biochemistry; Arginine; Enzyme; Myelin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006581401,0.0001648181,0.0001985592,0.0001356758,0.0001297455,0.00003719176,0.0003807226,0.00008741456,0.00001681942],"category_scores_gemma":[0.0006233921,0.0001205995,0.00005003257,0.0006214019,0.0007192991,0.00004533739,0.0001298414,0.0001557682,0.00000126031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005536459,"about_ca_system_score_gemma":0.0002927788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008172856,"about_ca_topic_score_gemma":0.00001194274,"domain_scores_codex":[0.9982232,0.0001373398,0.0003141053,0.0004467828,0.0005990793,0.000279498],"domain_scores_gemma":[0.9988136,0.00001674469,0.0002776741,0.0004726939,0.0003395043,0.00007976191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000715619,0.0001119016,0.0005135542,0.0003396593,0.00001089653,7.986809e-7,0.0001116854,0.00006438774,0.9958069,0.0000678795,0.00000790532,0.002892893],"study_design_scores_gemma":[0.0005963636,0.0006210574,0.002243082,0.0002799152,0.000009142676,0.00001149232,0.00007425909,0.002809269,0.9929541,0.00007814052,0.0001938006,0.000129352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928783,0.0002525492,0.004915769,0.0001513839,0.00002687105,0.001580677,0.000006395142,0.000005230463,0.0001827967],"genre_scores_gemma":[0.9976577,0.00002143292,0.002065139,0.00001333895,0.00001128052,0.00012056,0.000005829974,0.00001348816,0.00009122187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004779382,"threshold_uncertainty_score":0.4917904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004884844783018555,"score_gpt":0.2519024845294764,"score_spread":0.2470176397464579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}