{"id":"W2134248007","doi":"10.1093/intimm/14.3.309","title":"Overexpression of rab7 enhances the kinetics of antigen processing and presentation with MHC class II molecules in B cells","year":2002,"lang":"en","type":"article","venue":"International Immunology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"","keywords":"Endosome; Antigen processing; Cell biology; Antigen presentation; CD40; MHC class II; Endocytic cycle; Antigen; MHC class I; Cross-presentation; Antigen-presenting cell; Major histocompatibility complex; Biology; T cell; Chemistry; Immune system; Intracellular; Cytotoxic T cell; Immunology; Cell; Endocytosis; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003398458,0.0000556015,0.00006978581,0.00003865703,0.00001678404,0.000003876288,0.0001017408,0.00006095369,0.0000280754],"category_scores_gemma":[0.000007690619,0.0000404998,0.00001728595,0.00003648845,0.0001363251,0.000005818072,0.00003318903,0.00004278238,2.2028e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003479512,"about_ca_system_score_gemma":0.000005814702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003051198,"about_ca_topic_score_gemma":0.00003177029,"domain_scores_codex":[0.9995767,0.00002278309,0.0001538148,0.0001081531,0.00007877032,0.00005974575],"domain_scores_gemma":[0.9997303,0.000007797656,0.0001095502,0.00007525869,0.00007097876,0.000006068777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001027687,0.0000680214,0.004287277,0.000008882174,0.00002648398,6.241916e-7,0.0003059769,0.0000940197,0.9932574,0.00007077491,0.000004504352,0.001773285],"study_design_scores_gemma":[0.0003550453,0.0001961828,0.01806358,0.00003583039,0.000004668551,0.000005313051,0.0001007803,0.0007212406,0.9776831,0.0000512398,0.002738608,0.00004441549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943292,0.001500464,0.003259636,0.0001213126,0.00004331312,0.00007185594,0.00000562681,0.000001584805,0.000666965],"genre_scores_gemma":[0.9986817,0.000798951,0.0002398372,0.00001371112,0.0000186358,0.000004636599,0.0001150957,0.000004850191,0.0001226231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01557428,"threshold_uncertainty_score":0.1651534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007551896769067081,"score_gpt":0.2259545160489963,"score_spread":0.2184026192799292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}