{"id":"W2134285290","doi":"10.1038/nm.2513","title":"Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells","year":2011,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":918,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Child and Family Research Institute; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Proglucagon; Endocrinology; Internal medicine; Insulin; Secretion; Alpha cell; Enteroendocrine cell; Glucagon; Glucagon-like peptide-1; Insulin oscillation; Type 2 diabetes; Diabetes mellitus; Biology; Hormone; Chemistry; Islet; Medicine; Endocrine system; Beta cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003838388,0.0006368791,0.000384692,0.0004216368,0.0001804222,0.0006137617,0.0002530003,0.0003954781,0.004154261],"category_scores_gemma":[0.0005035482,0.0002608942,0.0007587174,0.0002573473,0.0003595231,0.0004081157,0.000377034,0.00158838,0.001135806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002134878,"about_ca_system_score_gemma":0.0001925803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002095028,"about_ca_topic_score_gemma":0.0002185394,"domain_scores_codex":[0.9996289,0.0001480897,0.00004665084,0.00004264565,0.00005072592,0.00008293158],"domain_scores_gemma":[0.9993037,0.0002802514,0.0000753518,0.00008238379,0.00005393008,0.0002042896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006631596,0.000276759,0.0008744801,0.0001112785,0.00001581081,0.0001740154,0.00005602944,0.00007612515,0.9862279,0.00008448704,0.0002279699,0.005243514],"study_design_scores_gemma":[0.0008997264,0.004447148,0.009297681,0.00002937094,0.00006006089,0.0005428016,0.0001118815,0.0007280503,0.9805108,0.0001663782,0.003190181,0.00001600821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878819,0.004256256,0.001867922,0.0007410671,0.0004056184,0.00003654646,0.0004317858,0.0001760322,0.004202944],"genre_scores_gemma":[0.9923236,0.001239418,0.002112615,0.0003174366,0.0002710703,0.00004244088,0.0005053596,0.00004406971,0.003143998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004154261,"threshold_uncertainty_score":0.01389742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0112549192233638,"score_gpt":0.2537833229968687,"score_spread":0.2425284037735049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}