{"id":"W2134338037","doi":"10.1242/jcs.134692","title":"N-WASP-directed actin polymerization activates p130Cas phosphorylation and lamellipodium spreading","year":2014,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; National Eye Institute; Canadian Institutes of Health Research","keywords":"Biology; Lamellipodium; Actin; Phosphorylation; Cell biology; Polymerization; Wiskott–Aldrich syndrome protein; Actin cytoskeleton; Biochemistry; Cytoskeleton; Polymer; Materials science; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006036854,0.0002576908,0.0001065675,0.0001481447,0.0001266226,0.0001377624,0.00009063734,0.0001583397,0.001004967],"category_scores_gemma":[0.00009708439,0.0001136196,0.0002144833,0.00008565094,0.0001684943,0.0001042125,0.0001984308,0.0004001466,0.0001794585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002654795,"about_ca_system_score_gemma":0.0001417879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003988973,"about_ca_topic_score_gemma":0.0008483733,"domain_scores_codex":[0.9999303,0.000009157703,0.000003543792,0.00001255852,0.00002005502,0.00002446754],"domain_scores_gemma":[0.999951,0.00000795135,0.00001344699,0.000004826193,0.000004155473,0.00001851393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004496931,0.00001051204,0.0001003376,0.00001419848,0.000001958644,0.00004897352,0.000004030321,0.00002607516,0.9992496,0.00004699736,0.00001884095,0.0004335017],"study_design_scores_gemma":[0.00001618634,0.0001190053,0.01217623,0.000004137239,0.000006762053,0.0002966691,0.00001399007,0.001119564,0.9852924,0.00006546457,0.0008866298,0.000002907743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997148,0.0004526719,0.001235629,0.00005455036,0.00001296206,0.0000205945,0.0001066692,0.00002281809,0.0009462547],"genre_scores_gemma":[0.9980183,0.0002219418,0.0007390147,0.00002170339,0.000005274583,0.00001659363,0.0001736693,0.000004537929,0.0007989838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004967,"threshold_uncertainty_score":0.00336194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004251661229620473,"score_gpt":0.2203389259087714,"score_spread":0.2160872646791509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}