{"id":"W2134375276","doi":"10.1074/jbc.m004134200","title":"Analysis of the Human Lumican Gene Promoter","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"National Eye Institute","keywords":"Promoter; Biology; Transcription (linguistics); Molecular biology; E-box; Response element; Gene; Repressor; Reporter gene; Upstream activating sequence; Transcription factor; CAAT box; TCF4; Exon; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110176,0.0002366486,0.0001746524,0.0003256624,0.0001791092,0.0002294859,0.0001396174,0.0001124447,0.002161505],"category_scores_gemma":[0.0001637878,0.0001175929,0.0002551419,0.0001928473,0.0001606357,0.0000789155,0.000110353,0.0003421458,0.001138744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000332468,"about_ca_system_score_gemma":0.0004085211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001875723,"about_ca_topic_score_gemma":0.002665127,"domain_scores_codex":[0.9999239,0.00000919176,0.000003564575,0.00002175433,0.00002588859,0.00001562115],"domain_scores_gemma":[0.9999171,0.00002940241,0.00001267625,0.000006399904,0.00001758004,0.00001684276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001328221,0.00001413063,0.0004839239,0.0000840592,0.000003688509,0.0001024421,0.00004352371,0.000139247,0.9945088,0.0002088875,0.00007650087,0.00420208],"study_design_scores_gemma":[0.00002586314,0.000181598,0.01138762,0.00004871904,0.00003184192,0.0005355511,0.00007032946,0.002617455,0.9671916,0.0002362012,0.0176623,0.00001090425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9346356,0.005474349,0.04296169,0.0003335965,0.00007106223,0.0001700609,0.006163743,0.0004380713,0.009751761],"genre_scores_gemma":[0.9282985,0.003011256,0.03339802,0.0002402526,0.00003711347,0.0001244686,0.02224322,0.0001080346,0.01253931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002161505,"threshold_uncertainty_score":0.007230937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01994191147294893,"score_gpt":0.2864745092684929,"score_spread":0.266532597795544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}