{"id":"W2134402496","doi":"10.1095/biolreprod.110.085712","title":"Hydrogen Peroxide Modifies Human Sperm Peroxiredoxins in a Dose-Dependent Manner","year":2010,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Sperm; Biology; Acrosome; Flagellum; Reactive oxygen species; Cell biology; Acrosome reaction; Hydrogen peroxide; Biochemistry; Cytosol; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002709267,0.0002651347,0.0001726953,0.0001796162,0.0001105036,0.0001861358,0.0001488369,0.0002408495,0.001424756],"category_scores_gemma":[0.0002098067,0.0001511756,0.0002154006,0.0001294184,0.000192019,0.000222484,0.0001771654,0.0002723426,0.0001839722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001299679,"about_ca_system_score_gemma":0.00009159413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002706719,"about_ca_topic_score_gemma":0.0003461543,"domain_scores_codex":[0.9998741,0.00003705194,0.000009224645,0.00003318446,0.00002581319,0.00002054393],"domain_scores_gemma":[0.9999043,0.00001639241,0.00003231356,0.00001243164,0.0000205046,0.00001414028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002698874,0.00005097606,0.0008137911,0.00007221814,0.00003282059,0.0000594828,0.00003766497,0.00003509854,0.9960737,0.00004936299,0.00007990101,0.002425039],"study_design_scores_gemma":[0.00003569447,0.001494362,0.01759011,0.000008143539,0.0000489149,0.0005593958,0.00004506776,0.0003474679,0.9765202,0.0001044804,0.003239362,0.000006735321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869108,0.007607063,0.004021714,0.0001744554,0.00008502607,0.00004741448,0.0001656485,0.00005948379,0.0009284567],"genre_scores_gemma":[0.9931712,0.002359515,0.001647958,0.0001060944,0.0000297957,0.00002430419,0.0003210851,0.000009964834,0.002330055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424756,"threshold_uncertainty_score":0.004766285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321567172936654,"score_gpt":0.2833445385740084,"score_spread":0.2701288668446418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}