{"id":"W2134430146","doi":"10.1111/j.1600-0463.2004.apm11211-1207.x","title":"Diagnostic PCR: validation and sample preparation are two sides of the same coin","year":2004,"lang":"en","type":"review","venue":"Apmis","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Standardization; Sample (material); Computer science; Computational biology; Medical physics; Medicine; Risk analysis (engineering); Biotechnology; Biology; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001008828,0.0001720975,0.0003186319,0.00002316212,0.00006665364,0.00001176948,0.0001843488,0.0002342159,0.000007313693],"category_scores_gemma":[0.0003775272,0.0001228077,0.0001674237,0.00007813435,0.0001079422,0.000001379309,0.0001289873,0.0000853819,0.000002158665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001521059,"about_ca_system_score_gemma":0.00009710024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008005636,"about_ca_topic_score_gemma":0.00003596531,"domain_scores_codex":[0.999175,0.00009433753,0.0002683493,0.0002987655,0.00006138065,0.0001021883],"domain_scores_gemma":[0.9990308,0.0000956586,0.0003265558,0.0004720939,0.0000473016,0.0000275612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002821799,0.0004222483,0.001310381,0.01446211,0.0007586415,0.000003075158,0.0001084686,0.00007173998,0.01708185,0.009505733,0.005996797,0.9502507],"study_design_scores_gemma":[0.0001422624,0.00009669179,0.00008691115,0.001765105,0.0003395008,0.00003129346,0.000004833121,0.000001529005,0.01627942,0.001859815,0.9791496,0.0002430547],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002099305,0.993492,0.002965009,0.00006449893,0.00003916892,0.0009829609,0.0002301611,0.00001455841,0.0001123206],"genre_scores_gemma":[0.006838269,0.9907096,0.001320844,0.00005580954,0.00006999288,0.0002708924,0.0006308632,0.00002216971,0.00008155624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9731528,"threshold_uncertainty_score":0.5007953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02376393104029419,"score_gpt":0.3381328648367894,"score_spread":0.3143689337964952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}