{"id":"W2134460361","doi":"10.1371/journal.pmed.0050197","title":"SLC2A9 Is a High-Capacity Urate Transporter in Humans","year":2008,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":376,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Economic and Social Research Council; National Institutes of Health; Health and Safety Executive; University College London; British Heart Foundation; Wellcome Trust; Medical Research Council; John D. and Catherine T. MacArthur Foundation; American Diabetes Association","keywords":"Hyperuricemia; Benzbromarone; Endocrinology; Uric acid; Glucose transporter; Internal medicine; Organic anion transporter 1; Chemistry; Transporter; Cotransporter; Biology; Biochemistry; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002664785,0.0003381975,0.0008865768,0.000330866,0.00009044933,0.000002738137,0.0001854799,0.0002066097,0.003189528],"category_scores_gemma":[0.0001784415,0.0002547254,0.00009591016,0.0005870671,0.0004231708,0.0001236402,0.0000205524,0.0006741158,0.0002820159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001481295,"about_ca_system_score_gemma":0.00009984725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005701648,"about_ca_topic_score_gemma":0.00004708512,"domain_scores_codex":[0.997326,0.00005147809,0.0006827552,0.0005392334,0.0008492381,0.0005513221],"domain_scores_gemma":[0.9986569,0.00008757247,0.0001226965,0.0006787521,0.0001139191,0.0003402176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009160574,0.002682644,0.6587583,0.0009854255,0.0008786214,0.00759888,0.05548517,0.000005047553,0.1898346,0.0003936829,0.08120285,0.001258692],"study_design_scores_gemma":[0.01761041,0.001709476,0.934889,0.001493725,0.001073552,0.0007889988,0.0007810115,0.0002801164,0.01849291,0.0005044352,0.02164054,0.0007358773],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771859,0.0004388988,0.00008982873,0.0123924,0.0002362394,0.0005825264,0.00001398795,0.0001608172,0.008899388],"genre_scores_gemma":[0.9878336,0.0003579261,0.0007184517,0.007029282,0.0007476322,0.00004596457,0.00005239911,0.00005782038,0.003156991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2761306,"threshold_uncertainty_score":0.9999905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06912563106737611,"score_gpt":0.2542309897597714,"score_spread":0.1851053586923953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}