{"id":"W2134460361","doi":"10.1371/journal.pmed.0050197","title":"SLC2A9 Is a High-Capacity Urate Transporter in Humans","year":2008,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":376,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Economic and Social Research Council; National Institutes of Health; Health and Safety Executive; University College London; British Heart Foundation; Wellcome Trust; Medical Research Council; John D. and Catherine T. MacArthur Foundation; American Diabetes Association","keywords":"Hyperuricemia; Benzbromarone; Endocrinology; Uric acid; Glucose transporter; Internal medicine; Organic anion transporter 1; Chemistry; Transporter; Cotransporter; Biology; Biochemistry; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425671,0.0002470653,0.0002317878,0.0001814146,0.0002599519,0.0003043175,0.0001266063,0.0004468598,0.004388003],"category_scores_gemma":[0.0002655425,0.00005820284,0.000203331,0.0003231107,0.0001737253,0.0001792167,0.0001428645,0.0002243701,0.0006038472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750448,"about_ca_system_score_gemma":0.0001342846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001307949,"about_ca_topic_score_gemma":0.0008499812,"domain_scores_codex":[0.9998844,0.00002319049,0.00001050314,0.00004831565,0.00002248061,0.00001111371],"domain_scores_gemma":[0.9999356,0.00001058538,0.0000219111,0.000004759977,0.00001520165,0.00001177537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003853024,0.0003674907,0.3956735,0.001157867,0.0008516284,0.01207329,0.0005233639,0.0005184358,0.3947743,0.003605547,0.02534418,0.1612573],"study_design_scores_gemma":[0.0002406375,0.001390826,0.8009445,0.0002104251,0.0005693318,0.04247614,0.0003486765,0.002519661,0.03311314,0.002148039,0.1159777,0.00006084263],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587494,0.01531409,0.005823858,0.002104456,0.0002656683,0.00008168676,0.005053128,0.0004138888,0.01219387],"genre_scores_gemma":[0.9904245,0.00229837,0.002183935,0.0005771859,0.00006913675,0.00004066437,0.001853634,0.0000336148,0.002518984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004388003,"threshold_uncertainty_score":0.01467931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06912563106737611,"score_gpt":0.2542309897597714,"score_spread":0.1851053586923953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}