{"id":"W2134477305","doi":"10.4049/jimmunol.1103527","title":"EVI1 Acts as an Inducible Negative-Feedback Regulator of NF-κB by Inhibiting p65 Acetylation","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute on Deafness and Other Communication Disorders; Biotechnology and Biological Sciences Research Council","keywords":"Regulator; Acetylation; Negative regulator; Chemistry; Cell biology; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001247975,0.000140737,0.0002381453,0.00006660573,0.00008655225,0.000008553411,0.0003285051,0.0002166887,0.00005158487],"category_scores_gemma":[0.0005213565,0.0001043163,0.00008396037,0.0001099714,0.000187233,0.00003173182,0.0001118015,0.0002762772,0.00001045387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000276456,"about_ca_system_score_gemma":0.0001369902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000241471,"about_ca_topic_score_gemma":0.000003018061,"domain_scores_codex":[0.9986015,0.0003883054,0.0004644885,0.0001050969,0.0001539458,0.0002866719],"domain_scores_gemma":[0.9985231,0.0000719347,0.000768366,0.0002996392,0.000254452,0.00008254068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000312404,0.00009089706,0.0005013002,0.000006653883,0.0001306183,5.229463e-7,0.0006581872,0.00003432865,0.9963903,0.0001415397,0.0005027861,0.001230466],"study_design_scores_gemma":[0.0006955235,0.0008824028,0.00156102,0.00004097342,0.00004655026,0.0002471224,0.0006239424,0.000004676147,0.9933715,0.0002560413,0.002162921,0.0001073399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949563,0.003681691,0.0002644669,0.0002731936,0.0002562739,0.0000882135,0.000005622718,0.000004490194,0.0004697353],"genre_scores_gemma":[0.9986233,0.000223062,0.0005118061,0.0001374817,0.0003178816,0.000001129029,0.00001252461,0.00002330378,0.0001495631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003666935,"threshold_uncertainty_score":0.4253894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628171898682645,"score_gpt":0.2615181198936583,"score_spread":0.2452364009068319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}