{"id":"W2134495709","doi":"10.1186/s13568-014-0063-6","title":"Reduced catabolic protein expression in Clostridium butyricum DSM 10702 correlate with reduced 1,3-propanediol synthesis at high glycerol loading","year":2014,"lang":"en","type":"article","venue":"AMB Express","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Ministère des relations internationales et de la Francophonie; Genome Canada","keywords":"Clostridium butyricum; Glycerol; 1,3-Propanediol; Catabolism; Propanediol; Microbiology; Biology; Chemistry; Protein expression; Food science; Biochemistry; Gene; Metabolism; Fermentation; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002777878,0.0003282584,0.0003338228,0.0001070968,0.0001176546,0.00003140677,0.0002708799,0.0002672172,0.00002190474],"category_scores_gemma":[0.0002757681,0.0002720865,0.00006563648,0.0001867578,0.00007115796,0.00001491255,0.0001573154,0.0002053155,0.0000238215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004508803,"about_ca_system_score_gemma":0.00003539229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001799654,"about_ca_topic_score_gemma":0.00001688473,"domain_scores_codex":[0.9981273,0.0001449637,0.0003250953,0.0007442185,0.0001854939,0.0004728924],"domain_scores_gemma":[0.998934,0.00001399379,0.0001596627,0.0006883511,0.00007770582,0.0001262613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004481346,0.00006449647,0.00007829903,0.00004838812,0.00002155043,0.000003595764,0.00006778286,0.0007039819,0.9965373,0.00001130846,0.0005137489,0.001501393],"study_design_scores_gemma":[0.0007424247,0.0001716547,0.0007486985,0.0002596398,0.00002523469,0.00003489956,0.00002236403,0.00009247758,0.9897176,0.000004595513,0.007787933,0.0003924689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973673,0.0003360251,0.000977461,0.0001475248,0.0004186648,0.0005278515,0.00001930924,0.00006315632,0.000142748],"genre_scores_gemma":[0.9957744,0.00007917024,0.001686511,0.000030227,0.0007933351,0.0002316659,0.00008992925,0.00006300699,0.001251778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007274184,"threshold_uncertainty_score":0.9999731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004159607433932923,"score_gpt":0.1862803141273777,"score_spread":0.1821207066934448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}