{"id":"W2134495709","doi":"10.1186/s13568-014-0063-6","title":"Reduced catabolic protein expression in Clostridium butyricum DSM 10702 correlate with reduced 1,3-propanediol synthesis at high glycerol loading","year":2014,"lang":"en","type":"article","venue":"AMB Express","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Ministère des relations internationales et de la Francophonie; Genome Canada","keywords":"Clostridium butyricum; Glycerol; 1,3-Propanediol; Catabolism; Propanediol; Microbiology; Biology; Chemistry; Protein expression; Food science; Biochemistry; Gene; Metabolism; Fermentation; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112024,0.0006457942,0.0002990963,0.0004242805,0.0002043981,0.0004629675,0.0001806561,0.00034058,0.0006450096],"category_scores_gemma":[0.0001889017,0.0002015336,0.0003407786,0.0006289569,0.0001876195,0.0001610143,0.0002847768,0.0004825021,0.0003192608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004807072,"about_ca_system_score_gemma":0.0005254601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006184907,"about_ca_topic_score_gemma":0.003972268,"domain_scores_codex":[0.9997244,0.0000191111,0.00003122533,0.00004563229,0.0001057716,0.0000737865],"domain_scores_gemma":[0.9998318,0.00002195103,0.00004406592,0.00001198894,0.00003858019,0.0000515762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005952769,0.0000158229,0.0006643144,0.00003196588,0.000003380927,0.00003692973,0.00001202664,0.00002739889,0.9986752,0.000009614486,0.00003182825,0.000432072],"study_design_scores_gemma":[0.00001954178,0.0003710254,0.1125973,0.00002300811,0.00004344755,0.000488406,0.0002630056,0.0009844393,0.8837777,0.00005078477,0.001363456,0.00001799679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960759,0.0004720822,0.0006738764,0.0001079752,0.00002124618,0.0000183076,0.001819291,0.00003671451,0.0007746053],"genre_scores_gemma":[0.9886004,0.0005849289,0.002334519,0.0001505217,0.000007495236,0.0000601281,0.006102218,0.00002785833,0.002131775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006184907,"threshold_uncertainty_score":0.01229781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004159607433932923,"score_gpt":0.1862803141273777,"score_spread":0.1821207066934448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}