{"id":"W2134503542","doi":"10.1039/c1an15352h","title":"A single DNA aptamer functions as a biosensor for ricin","year":2011,"lang":"en","type":"article","venue":"The Analyst","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Centers for Disease Control and Prevention; U.S. Department of Homeland Security","keywords":"Ricin; Aptamer; Chemistry; DNA; Biochemistry; Biosensor; Toxin; Detection limit; Computational biology; Molecular biology; Biology; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032686,0.0004985188,0.0003928937,0.0003324803,0.0001864608,0.0003246531,0.0003931277,0.0007564793,0.000825134],"category_scores_gemma":[0.0003231816,0.0001931636,0.0002372565,0.0002197488,0.0003225281,0.0003178077,0.0002467478,0.0005523489,0.0006812302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004175032,"about_ca_system_score_gemma":0.0001988126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001992466,"about_ca_topic_score_gemma":0.0002902253,"domain_scores_codex":[0.9996586,0.00003179925,0.00001938814,0.0001440425,0.0001009151,0.00004525274],"domain_scores_gemma":[0.9997624,0.00005734415,0.00006601134,0.00002268365,0.00004087635,0.00005075315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001763849,0.000009490945,0.00009281009,0.00001323593,0.000001799026,0.00001514533,0.0000139316,0.00006740747,0.9981828,0.00005380951,0.00001685912,0.001515071],"study_design_scores_gemma":[0.000002638956,0.0000894274,0.0002468459,0.000001949671,0.000003276679,0.0001208148,0.000007507369,0.0008608403,0.9981421,0.0000251898,0.0004968198,0.000002495289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9412141,0.001334453,0.05224882,0.0003270765,0.00006859758,0.0001264639,0.0002896122,0.0006358082,0.003755174],"genre_scores_gemma":[0.9638578,0.0005283981,0.03014561,0.00014846,0.00001380922,0.00008120675,0.0002761176,0.00004725874,0.004901347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000825134,"threshold_uncertainty_score":0.003029168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03852270690736854,"score_gpt":0.2339423183701971,"score_spread":0.1954196114628286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}