{"id":"W2134513851","doi":"10.1091/mbc.e07-01-0070","title":"Small Interfering RNA-mediated Silencing Induces Target-dependent Assembly of GW/P Bodies","year":2007,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Dental and Craniofacial Research; Breast Cancer Research Foundation; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Arthritis Society","keywords":"RNA interference; Gene knockdown; Biology; Small interfering RNA; Gene silencing; Trans-acting siRNA; Cell biology; RNA silencing; RNA; Transfection; Small hairpin RNA; RNA-induced silencing complex; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002993651,0.000462707,0.0002992723,0.0003329742,0.0001771736,0.0004174819,0.0002338549,0.0003091576,0.0008435461],"category_scores_gemma":[0.0003175709,0.0002762838,0.0004100626,0.0001568118,0.0005003233,0.0003835372,0.0004652273,0.0007830465,0.0007764206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003701197,"about_ca_system_score_gemma":0.0002064441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001933164,"about_ca_topic_score_gemma":0.0002969596,"domain_scores_codex":[0.9998105,0.00003619975,0.00002256336,0.00005183891,0.00004692751,0.000031943],"domain_scores_gemma":[0.9996781,0.00009522241,0.00009492539,0.00005484594,0.00002664647,0.00005010319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002075235,0.000006063597,0.0000425186,0.00001556181,0.000002264515,0.00005635664,0.000007844073,0.00002199417,0.9991794,0.0001561947,0.00002665824,0.0004643742],"study_design_scores_gemma":[0.00000665911,0.00004565895,0.0008160516,0.000002298342,0.000005472283,0.0001420982,0.000006827013,0.0005184807,0.9969278,0.00006769329,0.00145905,0.000001908526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9503223,0.002115693,0.04157224,0.0002254959,0.00008573711,0.0001244969,0.0004153737,0.0007718151,0.0043668],"genre_scores_gemma":[0.9803103,0.001027217,0.0131349,0.00008589925,0.00002005967,0.0001009534,0.0007743772,0.000194214,0.004352064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008435461,"threshold_uncertainty_score":0.002821982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314383376155531,"score_gpt":0.2412224912313521,"score_spread":0.2280786574697967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}