{"id":"W2134543408","doi":"10.1093/neuonc/nou239.2","title":"BI-02 * FUNCTIONAL CHARACTERIZATION OF NOVEL BIOMARKERS IN SELECTING FOR SUBTYPE SPECIFIC MEDULLOBLASTOMA PHENOTYPES","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Manitoba","funders":"","keywords":"Sonic hedgehog; Medulloblastoma; Phenotype; Biology; Cancer research; Flow cytometry; Cell sorting; Wnt signaling pathway; Population; Transcriptome; Cell; Computational biology; Molecular biology; Genetics; Gene expression; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003204143,0.000374749,0.000277635,0.0005139026,0.0002096641,0.0007233177,0.0003263048,0.0003017624,0.003789776],"category_scores_gemma":[0.0002409845,0.0002044412,0.0002669025,0.0005236064,0.0001128328,0.0001844112,0.0002778614,0.0005301085,0.002045947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004381867,"about_ca_system_score_gemma":0.0003237542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001514224,"about_ca_topic_score_gemma":0.001969082,"domain_scores_codex":[0.9997074,0.00004085743,0.0000248338,0.00006487024,0.0001111005,0.00005104194],"domain_scores_gemma":[0.9998642,0.00001907819,0.00001661463,0.00001671173,0.00004565909,0.00003775641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001351276,0.00004416145,0.0009186459,0.00002815035,0.000007605375,0.0000176243,0.000009940738,0.00008566433,0.9942244,0.00008569653,0.0003467983,0.004096183],"study_design_scores_gemma":[0.00002074306,0.0003509824,0.01008213,0.000007707858,0.00002992483,0.0002504517,0.00003541985,0.004464761,0.974462,0.00006097979,0.01022562,0.000009204114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.971157,0.001644951,0.01246291,0.0002680591,0.00003998724,0.0002375316,0.003391905,0.0005547219,0.01024303],"genre_scores_gemma":[0.9247617,0.001004073,0.03561879,0.0002770545,0.00001817353,0.0005085194,0.0160314,0.000213763,0.02156665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003789776,"threshold_uncertainty_score":0.01267809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02694358005785323,"score_gpt":0.2629105043238488,"score_spread":0.2359669242659956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}