{"id":"W2134543408","doi":"10.1093/neuonc/nou239.2","title":"BI-02 * FUNCTIONAL CHARACTERIZATION OF NOVEL BIOMARKERS IN SELECTING FOR SUBTYPE SPECIFIC MEDULLOBLASTOMA PHENOTYPES","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Manitoba","funders":"","keywords":"Sonic hedgehog; Medulloblastoma; Phenotype; Biology; Cancer research; Flow cytometry; Cell sorting; Wnt signaling pathway; Population; Transcriptome; Cell; Computational biology; Molecular biology; Genetics; Gene expression; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003408937,0.0001388522,0.0002358859,0.0001096011,0.00006283981,0.000005849243,0.0001081961,0.000180037,0.00001025417],"category_scores_gemma":[0.000477143,0.0001440273,0.00006641488,0.0001673269,0.00009120965,0.000004098507,0.00006140952,0.00008136491,0.000003794761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003486619,"about_ca_system_score_gemma":0.0001105676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005152129,"about_ca_topic_score_gemma":0.00004925369,"domain_scores_codex":[0.9989065,0.00009687464,0.0003099556,0.0003595405,0.00008675963,0.0002403517],"domain_scores_gemma":[0.9992942,0.0001684497,0.000187736,0.0001556929,0.0001538835,0.00004001099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004059409,0.0001369365,0.00303271,0.00002459119,0.00004596462,6.650427e-7,0.00007551267,0.00007392152,0.9891229,0.0001182695,0.000293396,0.006669198],"study_design_scores_gemma":[0.001602629,0.001255808,0.01122045,0.00001114818,0.00001579101,0.0000145305,0.00004619353,0.0007141354,0.863167,0.00002154517,0.1217671,0.000163719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788901,0.00006040512,0.01938204,0.0002798641,0.0006463178,0.0002616914,0.00002335211,0.00001520136,0.0004410591],"genre_scores_gemma":[0.9978134,0.00003591895,0.001204088,0.0002992071,0.0004119104,0.00004878872,0.0001369938,0.00002798073,0.00002172446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1259559,"threshold_uncertainty_score":0.5873262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02694358005785323,"score_gpt":0.2629105043238488,"score_spread":0.2359669242659956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}