{"id":"W2134562563","doi":"10.1091/mbc.e13-10-0582","title":"SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1–matrix metalloproteinase (MT1-MMP) during invadopodium formation and tumor cell invasion","year":2014,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Matrix metalloproteinase; Cell biology; Vesicle; Metalloproteinase; Membrane protein; Transport protein; Viral matrix protein; Matrix (chemical analysis); Membrane; Cell membrane; Biochemistry; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005576827,0.0002436806,0.000359092,0.00007998371,0.0001142515,0.00001146903,0.0002369367,0.0002506073,0.000006091083],"category_scores_gemma":[0.0002288259,0.0001951403,0.000115924,0.0001356015,0.0001832704,0.00001291667,0.0002895665,0.0001525327,0.000001562787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001301026,"about_ca_system_score_gemma":0.00004487895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003602802,"about_ca_topic_score_gemma":0.00001420144,"domain_scores_codex":[0.998403,0.0003833743,0.0004174085,0.0003711767,0.0001417613,0.0002832932],"domain_scores_gemma":[0.9989485,0.00001912354,0.0004552301,0.0003901226,0.0001050635,0.00008195695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001425277,0.0000828874,0.00005517919,0.000347184,0.00003599427,0.0000025191,0.0000574727,0.00002858281,0.9990944,0.00006677025,0.000005832032,0.0000806131],"study_design_scores_gemma":[0.001299327,0.0005459568,0.0000596053,0.00009014045,0.00007090867,0.00001452167,0.00003444889,0.0002220964,0.9970773,0.0002731613,0.000100892,0.0002115716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970574,0.001491345,0.0003990396,0.0000927704,0.00008927548,0.0006999339,0.0000168132,0.00001416246,0.000139293],"genre_scores_gemma":[0.9989333,0.0001025601,0.0006645522,0.00007431692,0.00003451597,0.00002542362,0.00006201807,0.00002952556,0.00007384174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002017068,"threshold_uncertainty_score":0.7957591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004524695570812703,"score_gpt":0.1987655687326604,"score_spread":0.1942408731618477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}