{"id":"W2134658642","doi":"10.1534/genetics.112.141051","title":"Genome Rearrangements Caused by Depletion of Essential DNA Replication Proteins in<i>Saccharomyces cerevisiae</i>","year":2012,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Occupational Cancer Research Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Versus Arthritis","keywords":"Biology; Genetics; Gene; DNA replication; Genome; Retrotransposon; Control of chromosome duplication; Origin recognition complex; Homologous recombination; Saccharomyces cerevisiae; Pre-replication complex; Eukaryotic DNA replication; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007765842,0.0003008673,0.0001835734,0.000214072,0.0001260909,0.0002491007,0.0001451785,0.0001412394,0.0004936911],"category_scores_gemma":[0.0001365457,0.0001574065,0.0001863812,0.0002255795,0.0001456898,0.00008765792,0.0001723902,0.0003121557,0.0001593307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003071521,"about_ca_system_score_gemma":0.0001795935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362627,"about_ca_topic_score_gemma":0.002439191,"domain_scores_codex":[0.999911,0.00001003761,0.00001400407,0.00001954438,0.00002575576,0.00001974123],"domain_scores_gemma":[0.9998535,0.00002761061,0.00006046249,0.00001622595,0.00001257438,0.00002967174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004502708,0.000006627563,0.0006693812,0.00001423338,0.000004977372,0.00003678938,0.000007007061,0.00005353502,0.9985639,0.00002221583,0.00001391747,0.0005623206],"study_design_scores_gemma":[0.000008683166,0.0001010885,0.01998295,0.000005859701,0.0000332552,0.0004178394,0.00003374541,0.0006114803,0.9778295,0.00004640834,0.000924805,0.000004479902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982231,0.0003300933,0.0007994859,0.00002065087,0.000003702907,0.000006987056,0.0003019842,0.00004810817,0.0002659624],"genre_scores_gemma":[0.9972559,0.0003367109,0.001066398,0.00002908341,0.00000214759,0.000009910073,0.0008312743,0.00003039043,0.0004381673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001362627,"threshold_uncertainty_score":0.002709389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01045771072844531,"score_gpt":0.2482406475425219,"score_spread":0.2377829368140766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}