{"id":"W2134658642","doi":"10.1534/genetics.112.141051","title":"Genome Rearrangements Caused by Depletion of Essential DNA Replication Proteins in<i>Saccharomyces cerevisiae</i>","year":2012,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Occupational Cancer Research Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Versus Arthritis","keywords":"Biology; Genetics; Gene; DNA replication; Genome; Retrotransposon; Control of chromosome duplication; Origin recognition complex; Homologous recombination; Saccharomyces cerevisiae; Pre-replication complex; Eukaryotic DNA replication; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002640792,0.0001249085,0.0001275114,0.00004056193,0.00002598994,0.000008685887,0.0001708461,0.0001375392,0.00002802332],"category_scores_gemma":[0.0000351556,0.0001359779,0.00005000715,0.000097149,0.00003200623,0.00000525736,0.00009457082,0.0000476744,0.00001185249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001871527,"about_ca_system_score_gemma":0.00002493312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009766645,"about_ca_topic_score_gemma":0.00001536536,"domain_scores_codex":[0.9989414,0.00006393831,0.0002751842,0.0002918368,0.000166396,0.0002612012],"domain_scores_gemma":[0.9991137,0.000002948577,0.0001482707,0.0006074512,0.00005770426,0.00006997352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001686131,0.000111707,0.009950535,0.00003316614,0.00002106552,1.825428e-7,0.00006216337,0.000007972677,0.9888391,0.00001675485,0.0002653876,0.000675137],"study_design_scores_gemma":[0.0003762419,0.000126785,0.0162519,0.000009426739,0.00001579997,0.000002404412,0.0000278916,0.00001252471,0.9686875,0.00002816165,0.01432149,0.0001398574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952118,0.001552887,0.002336235,0.00004620342,0.00008940419,0.0004899052,0.00003344471,0.00001196863,0.0002281181],"genre_scores_gemma":[0.9965451,0.0003482708,0.002331262,0.00005244914,0.0001588729,0.00006790247,0.0002980571,0.00002748683,0.0001705756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02015156,"threshold_uncertainty_score":0.5545018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01045771072844531,"score_gpt":0.2482406475425219,"score_spread":0.2377829368140766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}