{"id":"W2134673249","doi":"10.5167/uzh-58181","title":"Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Lovastatin; Cerivastatin; Statin; Apoptosis; Fluvastatin; Pharmacology; Mevalonate pathway; Larrea; HMG-CoA reductase; Atorvastatin; Cancer research; Reductase; Biology; Cholesterol; Simvastatin; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002483276,0.000238406,0.0005588767,0.0002644826,0.0001397215,0.0002777244,0.0001687483,0.0002960116,0.001204655],"category_scores_gemma":[0.0002018346,0.00009917296,0.0002842481,0.0001882725,0.0001550096,0.0002444005,0.0001759323,0.0005868429,0.0002476021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002929907,"about_ca_system_score_gemma":0.0003005642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003180311,"about_ca_topic_score_gemma":0.0005158532,"domain_scores_codex":[0.999731,0.00004950933,0.00004570928,0.00004173491,0.0000767925,0.00005522233],"domain_scores_gemma":[0.9998263,0.00002973421,0.00003036824,0.00003568718,0.00002940465,0.00004847789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005217741,0.00012381,0.0001598052,0.00004531722,0.00001149151,0.00003695916,0.0000176242,0.00006227649,0.9959561,0.00008463393,0.00005718225,0.002922958],"study_design_scores_gemma":[0.00008327332,0.002340436,0.00232029,0.00000336717,0.00002284931,0.0002956073,0.00001823249,0.0003379331,0.9923398,0.00003422345,0.002200253,0.000003737914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921736,0.00435058,0.001268034,0.0001576695,0.00007322682,0.00004097741,0.0002275066,0.0001025281,0.001605952],"genre_scores_gemma":[0.9951819,0.001552414,0.001049505,0.00008322225,0.00003637383,0.00003979939,0.000390657,0.00001643047,0.001649786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001204655,"threshold_uncertainty_score":0.004030049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01616375498459036,"score_gpt":0.2148639645910226,"score_spread":0.1987002096064323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}