{"id":"W2134688453","doi":"10.1016/j.bbamcr.2007.09.004","title":"The orphan nuclear receptor Rev-erbβ recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter","year":2007,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Nuclear receptor; Repressor; Psychological repression; HDAC1; Histone deacetylase; Acetylation; Transcription factor; Chemistry; Orphan receptor; Molecular biology; Transcription (linguistics); HDAC8; Activator (genetics); Histone; Receptor; Cell biology; Biology; Gene; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003100948,0.0007033977,0.0004582677,0.00063122,0.0004414869,0.0009153112,0.0004759162,0.0003709714,0.003183726],"category_scores_gemma":[0.0003939106,0.0006588394,0.0007352364,0.0002369235,0.0005058573,0.0004217489,0.0008509788,0.001092598,0.002698613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001264522,"about_ca_system_score_gemma":0.0004075749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002161484,"about_ca_topic_score_gemma":0.003737777,"domain_scores_codex":[0.9995531,0.00003381355,0.0000230754,0.0001336731,0.00009674003,0.000159492],"domain_scores_gemma":[0.9996698,0.00004081776,0.00007591744,0.00004312979,0.0000630699,0.0001072615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001625286,0.00001839864,0.0006854266,0.00003962396,0.00001174887,0.0001150273,0.00005478593,0.00003110316,0.9954998,0.0004038415,0.0003961873,0.002581507],"study_design_scores_gemma":[0.00006783409,0.0001065144,0.04627329,0.00003760634,0.00004477625,0.0007069779,0.0003288757,0.001220359,0.939918,0.0006789691,0.01059482,0.0000220667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9462544,0.0132581,0.01782334,0.0008819693,0.0005788804,0.00007862593,0.001908931,0.0008113298,0.01840438],"genre_scores_gemma":[0.9804726,0.002125579,0.003773021,0.0003378795,0.00006457041,0.00006381382,0.002396807,0.0002652461,0.01050052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003183726,"threshold_uncertainty_score":0.01065063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04728906641059633,"score_gpt":0.3350698729258633,"score_spread":0.2877808065152669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}