{"id":"W2134688453","doi":"10.1016/j.bbamcr.2007.09.004","title":"The orphan nuclear receptor Rev-erbβ recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter","year":2007,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Nuclear receptor; Repressor; Psychological repression; HDAC1; Histone deacetylase; Acetylation; Transcription factor; Chemistry; Orphan receptor; Molecular biology; Transcription (linguistics); HDAC8; Activator (genetics); Histone; Receptor; Cell biology; Biology; Gene; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003126945,0.0004548606,0.0003743123,0.0003818819,0.001254062,0.0007739377,0.001347104,0.0002674456,0.0001302678],"category_scores_gemma":[0.000716751,0.0003551803,0.0002035842,0.001433234,0.0007301207,0.000199794,0.00108755,0.001213142,0.0007638969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001458964,"about_ca_system_score_gemma":0.0001215068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000882962,"about_ca_topic_score_gemma":0.000008950446,"domain_scores_codex":[0.9935945,0.001106356,0.0005661512,0.001410508,0.001650771,0.001671691],"domain_scores_gemma":[0.9971004,0.0005080934,0.0001684663,0.001245068,0.0002366454,0.0007413642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004029722,0.0001612961,4.429047e-7,0.00004720444,0.00001499111,0.00004532482,0.0007929255,7.485061e-7,0.985901,0.001558876,0.003362773,0.007711429],"study_design_scores_gemma":[0.0003998697,0.000586519,0.00006332051,0.00009959234,0.00001048778,0.000009603134,0.0001401235,0.0000815361,0.9374974,0.0004769263,0.06020848,0.0004261719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841793,0.00009543615,0.00004579138,0.006876927,0.0001999543,0.001777718,0.0000193831,0.0001355841,0.006669869],"genre_scores_gemma":[0.9942712,0.000300276,0.0009525147,0.0009847664,0.0002622155,0.00004575284,0.000006907503,0.0001983825,0.002977981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05684571,"threshold_uncertainty_score":0.99989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04728906641059633,"score_gpt":0.3350698729258633,"score_spread":0.2877808065152669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}