{"id":"W2134692691","doi":"10.1186/1476-4598-11-52","title":"The emerging role of histone lysine demethylases in prostate cancer","year":2012,"lang":"en","type":"review","venue":"Molecular Cancer","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia; Pancreas Centre (Canada)","funders":"Prostate Cancer Canada","keywords":"Biology; Epigenetics; Cancer research; Histone; EZH2; DNA methylation; Histone methyltransferase; Prostate cancer; Histone methylation; Regulation of gene expression; Demethylase; Cancer; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004159769,0.0003691653,0.0005321271,0.0004825199,0.0001891041,0.0006541088,0.000395464,0.0006983604,0.001552526],"category_scores_gemma":[0.0003571664,0.0001301963,0.000313119,0.0007202773,0.0005283923,0.0006219118,0.0005155971,0.001495864,0.0004984537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004298587,"about_ca_system_score_gemma":0.0005267712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006531971,"about_ca_topic_score_gemma":0.0007697762,"domain_scores_codex":[0.9998337,0.00002906425,0.00001121254,0.00004503045,0.00005609761,0.00002477675],"domain_scores_gemma":[0.9997525,0.00007293349,0.0000570096,0.00001206785,0.00005663644,0.00004895052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005569261,0.0001845454,0.004889633,0.007887871,0.0001962494,0.001045172,0.0002045899,0.001053212,0.05855659,0.01536128,0.02169061,0.8883734],"study_design_scores_gemma":[0.00008988514,0.001189027,0.04004219,0.001087579,0.0003577896,0.005915409,0.0003634141,0.00176123,0.02012136,0.01908235,0.9098929,0.00009693113],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004607191,0.9899964,0.001211138,0.001878263,0.0003833905,0.000006926652,0.0001088542,0.00003731113,0.00177053],"genre_scores_gemma":[0.0481421,0.9461382,0.001431282,0.001264146,0.001353711,0.00001730662,0.0002260883,0.000005943872,0.001421214],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001552526,"threshold_uncertainty_score":0.00519371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02045001622833733,"score_gpt":0.3679816480119453,"score_spread":0.347531631783608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}