{"id":"W2134699792","doi":"10.1161/01.res.0000129255.19569.8f","title":"Malonyl Coenzyme A Decarboxylase Inhibition Protects the Ischemic Heart by Inhibiting Fatty Acid Oxidation and Stimulating Glucose Oxidation","year":2004,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Energy; University of Alberta","funders":"","keywords":"Beta oxidation; Internal medicine; Fatty acid; Endocrinology; Chemistry; In vivo; Coenzyme A; Cardiac function curve; Ex vivo; Ischemia; Malonyl-CoA; Biochemistry; Enzyme; Medicine; Biology; In vitro; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001079201,0.0001391349,0.000109215,0.0001076805,0.0004979806,0.000113531,0.00007341313,0.0002178173,0.00002714768],"category_scores_gemma":[0.0006963258,0.0001261014,0.00004502154,0.0003092178,0.0001556962,0.00002895328,0.000100391,0.0003016357,0.00002874744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006303279,"about_ca_system_score_gemma":0.0001047267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008222899,"about_ca_topic_score_gemma":0.00004793163,"domain_scores_codex":[0.9982933,0.0002893523,0.0002744358,0.0004619011,0.0003544919,0.0003264613],"domain_scores_gemma":[0.9991958,0.00005451969,0.00009021621,0.0002549473,0.0003043041,0.0001002539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007406755,0.00003219981,0.00118685,0.0000229922,0.000007893367,0.000001435626,0.000105425,0.001231739,0.995415,0.0001596503,0.001002192,0.0007606068],"study_design_scores_gemma":[0.001043003,0.0001632129,0.002646086,0.00003779511,0.000005803698,0.00004655264,0.0001391412,0.001295296,0.9931599,0.0003484257,0.0009698966,0.000144854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9460846,0.00034152,0.05142928,0.00101342,0.00007076807,0.0008161395,0.000007754881,0.00002781457,0.0002087419],"genre_scores_gemma":[0.9976737,0.00002717013,0.001058503,0.0002407692,0.0002880447,0.0001300583,0.0005230391,0.00002372125,0.00003496822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05158916,"threshold_uncertainty_score":0.5142267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03420577938063356,"score_gpt":0.3148471199096833,"score_spread":0.2806413405290497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}