{"id":"W2134718821","doi":"10.1152/physrev.00026.2007","title":"Telomeres and Aging","year":2008,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":1181,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Telomere; Telomerase; Dyskeratosis congenita; Biology; Somatic cell; Telomerase RNA component; Senescence; Cell biology; Genome instability; Cell division; Genetics; Cancer research; DNA damage; Telomerase reverse transcriptase; Cell; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002255387,0.0007377689,0.00520153,0.0001393908,0.0001441521,0.00002177185,0.0002517839,0.0003671077,0.0002427725],"category_scores_gemma":[0.0007626278,0.0004003888,0.001011567,0.0004386964,0.0003136857,0.00005742187,0.0001936038,0.000808267,0.0007153475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006152339,"about_ca_system_score_gemma":0.0001176398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008261844,"about_ca_topic_score_gemma":4.992283e-7,"domain_scores_codex":[0.9968742,0.0003901906,0.00109979,0.000889284,0.0002346311,0.0005119527],"domain_scores_gemma":[0.9981859,0.0002721071,0.0004515259,0.0006813181,0.00004341262,0.0003657414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004112545,0.00007308412,0.000006386664,0.01732434,0.0000490061,0.00008331322,0.00001560346,4.708028e-9,0.00001742464,0.00005350233,0.0253976,0.9569756],"study_design_scores_gemma":[0.0001356425,0.0001490867,0.0001870788,0.01934358,0.000400883,0.0005423992,0.000002924814,6.977273e-7,9.798925e-7,0.00003110295,0.9787897,0.0004159587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003835531,0.9975647,0.000005367197,0.00004741643,0.0001242926,0.001579693,0.00001161338,0.0001117571,0.0005167926],"genre_scores_gemma":[0.00001299267,0.9969562,0.0006449311,0.0006077087,0.0005963758,0.0002018379,0.0001210175,0.000048575,0.0008103452],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9565597,"threshold_uncertainty_score":0.9998448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2177523532829415,"score_gpt":0.4130355656955551,"score_spread":0.1952832124126136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}