{"id":"W2134718821","doi":"10.1152/physrev.00026.2007","title":"Telomeres and Aging","year":2008,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":1181,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Telomere; Telomerase; Dyskeratosis congenita; Biology; Somatic cell; Telomerase RNA component; Senescence; Cell biology; Genome instability; Cell division; Genetics; Cancer research; DNA damage; Telomerase reverse transcriptase; Cell; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004303008,0.0009490937,0.0009188136,0.0009441966,0.0005181632,0.001324831,0.0006514831,0.001636444,0.004511724],"category_scores_gemma":[0.000678247,0.0001599497,0.0002797158,0.001179345,0.0008288074,0.001659491,0.001035248,0.001675134,0.003368892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007944476,"about_ca_system_score_gemma":0.001164266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000915223,"about_ca_topic_score_gemma":0.001031227,"domain_scores_codex":[0.9997653,0.00005059504,0.00002769908,0.0000450507,0.00007934865,0.00003203503],"domain_scores_gemma":[0.9998099,0.00005364237,0.00003829379,0.0000113178,0.00005421479,0.00003265253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001101892,0.00004766206,0.0003611246,0.005730792,0.00004900792,0.0004384121,0.0003250808,0.0003180435,0.005909114,0.01953305,0.0704002,0.8967774],"study_design_scores_gemma":[0.000008519602,0.00005490813,0.0008106732,0.0009720325,0.00002101525,0.001350471,0.00008935464,0.00002858396,0.0005546038,0.00651615,0.989583,0.00001066113],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001825781,0.9965234,0.0001385318,0.0004972238,0.000540172,0.00000289388,0.000008816215,0.00001327273,0.002093175],"genre_scores_gemma":[0.002806308,0.9921027,0.0002213702,0.0005885832,0.0006205133,0.000009369163,0.00003124249,0.000002823718,0.003617119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004511724,"threshold_uncertainty_score":0.01509321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2177523532829415,"score_gpt":0.4130355656955551,"score_spread":0.1952832124126136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}