{"id":"W2134751179","doi":"10.3390/genes5040887","title":"Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives","year":2014,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Canada Research Chairs; McGill University","keywords":"Biology; Mutagenesis; Genome; Gene; Genetics; Phenotype; Immunity; Forward genetics; Computational biology; Human genetics; Mutation; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003200609,0.0003950103,0.0007095306,0.0002578331,0.0001204347,0.00005590122,0.0001796545,0.0002899943,0.00002381854],"category_scores_gemma":[0.0001994065,0.0003741117,0.0001606979,0.0004706293,0.00003246003,0.000001727107,0.0002505084,0.0001231527,0.00001037156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003542644,"about_ca_system_score_gemma":0.00008442596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009969242,"about_ca_topic_score_gemma":0.0001532332,"domain_scores_codex":[0.9984922,0.0002642401,0.0002776201,0.0005855095,0.0000864804,0.000293976],"domain_scores_gemma":[0.9990317,0.00005008988,0.00006632227,0.0005337207,0.0001119884,0.0002062023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001226432,0.00002834765,0.00001283576,0.00230263,0.0003366478,0.000001119009,0.000315137,0.0001067532,0.02209017,0.00001840174,0.001873519,0.9729022],"study_design_scores_gemma":[0.00008621129,0.000188174,0.00006574296,0.0002478661,0.0002055591,0.0000347794,0.0001383284,0.000001985323,0.007938204,0.000003582927,0.9906249,0.0004646468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001877651,0.9103934,0.08693397,0.00001521601,0.0001375818,0.0004973128,0.00003309811,0.00003047247,0.00008133354],"genre_scores_gemma":[0.0001755674,0.9846337,0.01405598,0.00003499694,0.0003842673,0.00007083594,0.0001375044,0.00007153183,0.0004356599],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9887514,"threshold_uncertainty_score":0.9998711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05163272787417625,"score_gpt":0.3965359632209795,"score_spread":0.3449032353468032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}