{"id":"W2134751179","doi":"10.3390/genes5040887","title":"Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives","year":2014,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Canada Research Chairs; McGill University","keywords":"Biology; Mutagenesis; Genome; Gene; Genetics; Phenotype; Immunity; Forward genetics; Computational biology; Human genetics; Mutation; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001344825,0.001360705,0.0008644381,0.002133096,0.000273759,0.001029516,0.0008978923,0.001055424,0.001362929],"category_scores_gemma":[0.0005089816,0.0004614138,0.0005567186,0.001302454,0.0007441428,0.001038019,0.0005026445,0.002104295,0.001430496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000702482,"about_ca_system_score_gemma":0.0005372408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000568077,"about_ca_topic_score_gemma":0.0007351468,"domain_scores_codex":[0.9995485,0.0001009599,0.00005004913,0.00008191067,0.0001751801,0.00004340873],"domain_scores_gemma":[0.9997249,0.00009091925,0.00005757879,0.0000262518,0.00006410465,0.00003615594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002366149,0.0003321553,0.0009656831,0.009543475,0.0001389312,0.001006067,0.0002338257,0.001309967,0.6080254,0.04305933,0.01951288,0.3156357],"study_design_scores_gemma":[0.00003169601,0.0004350027,0.001896158,0.0006843848,0.0001612177,0.003007925,0.0000599055,0.001107933,0.2040917,0.006890572,0.7815462,0.00008730092],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01379581,0.8535097,0.1096356,0.003165104,0.001048136,0.0001999734,0.0009478655,0.00135692,0.01634102],"genre_scores_gemma":[0.04062893,0.8803856,0.06540912,0.001676916,0.000378888,0.0002805947,0.001344381,0.0002287186,0.009666713],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002133096,"threshold_uncertainty_score":0.007112205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05163272787417625,"score_gpt":0.3965359632209795,"score_spread":0.3449032353468032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}