{"id":"W2134796222","doi":"10.1002/btpr.1658","title":"Fed‐batch CHO cell t‐PA production and feed glutamine replacement to reduce ammonia production","year":2012,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Glutamine; Ammonia; Ammonia production; Production (economics); Chemistry; Food science; Biochemistry; Amino acid; Economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002299637,0.000230738,0.0001632529,0.0001201352,0.0002198422,0.00002744464,0.0001524183,0.0004020547,0.000009551057],"category_scores_gemma":[0.0001607274,0.0002133614,0.00004878474,0.0002325178,0.0002237776,0.00001477474,0.0002164563,0.0001476975,0.00002555049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003573408,"about_ca_system_score_gemma":0.0000293448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001398972,"about_ca_topic_score_gemma":0.00001213595,"domain_scores_codex":[0.9984401,0.00005463255,0.0002251214,0.0006783293,0.0001307274,0.0004710477],"domain_scores_gemma":[0.9989948,0.00000220073,0.0001251011,0.0006254083,0.00008601369,0.0001665305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003674947,0.0003874362,0.01390495,0.00005396508,0.00003643363,8.853077e-7,0.00005550419,0.000008071051,0.9543743,0.00003959111,0.01405734,0.01671405],"study_design_scores_gemma":[0.0002787331,0.0007179483,0.004532448,0.00002811403,0.00002663589,0.00006269995,0.00008411024,0.000003150701,0.9223779,0.00001681761,0.07161368,0.0002576914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900119,0.003558072,0.0001270352,0.00374239,0.001318054,0.001001294,0.000007520209,0.0001375172,0.0000961862],"genre_scores_gemma":[0.9948732,0.0003777067,0.001691296,0.0001198006,0.0008160866,0.0003860661,0.00003917915,0.00003305736,0.001663596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05755634,"threshold_uncertainty_score":0.8700625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0089032296707671,"score_gpt":0.2627272405740518,"score_spread":0.2538240109032847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}