{"id":"W2134796222","doi":"10.1002/btpr.1658","title":"Fed‐batch CHO cell t‐PA production and feed glutamine replacement to reduce ammonia production","year":2012,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Glutamine; Ammonia; Ammonia production; Production (economics); Chemistry; Food science; Biochemistry; Amino acid; Economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211097,0.0006720389,0.0007378071,0.000267656,0.0001943851,0.0005938658,0.0007468317,0.0006266318,0.0004688594],"category_scores_gemma":[0.0002789754,0.0001641031,0.0006311216,0.0005566303,0.0001827673,0.0003347375,0.0004095485,0.0007015918,0.0004366831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005174603,"about_ca_system_score_gemma":0.0003921447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001860367,"about_ca_topic_score_gemma":0.002182466,"domain_scores_codex":[0.9996178,0.00006168893,0.00004316524,0.0000908433,0.0001497217,0.00003685744],"domain_scores_gemma":[0.9998474,0.00001903491,0.0000374809,0.00002545168,0.00004960282,0.00002108637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008760662,0.00003425023,0.0001341314,0.00004662795,0.000008255101,0.0000565886,0.000008920497,0.0001230877,0.9978435,0.0000231167,0.00003531414,0.001598748],"study_design_scores_gemma":[0.000009413217,0.0002661889,0.0007358319,0.000004206232,0.00002073943,0.000154651,0.00001113687,0.001068119,0.9962677,0.0000129709,0.001441071,0.000007977747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697263,0.002507572,0.02380634,0.0001498699,0.0001232728,0.0002097289,0.0008441533,0.0003750339,0.002257711],"genre_scores_gemma":[0.9348295,0.001705864,0.05562801,0.00009040341,0.00002615469,0.0002253473,0.002471916,0.00009303574,0.00492974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001860367,"threshold_uncertainty_score":0.003754437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0089032296707671,"score_gpt":0.2627272405740518,"score_spread":0.2538240109032847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}