{"id":"W2134812257","doi":"10.1039/c1md00260k","title":"Inhibitory effect of bortezomib on human multiple myeloma cells when combined with epigallocatechin-gallate (EGCG) analogs","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; U.S. Food and Drug Administration; Hong Kong Polytechnic University","keywords":"Bortezomib; Gallate; Multiple myeloma; Epigallocatechin gallate; Chemistry; Inhibitory postsynaptic potential; Cancer research; Pharmacology; Biochemistry; Medicine; Internal medicine; Polyphenol; Nuclear chemistry; Antioxidant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004569866,0.0004196665,0.0008198124,0.000286971,0.0001382658,0.00001280567,0.0002611025,0.0001690093,0.0003946218],"category_scores_gemma":[0.0001039106,0.0002798435,0.0001911624,0.0002109958,0.0002762848,0.00008082161,0.0001011843,0.0004419796,0.0001579074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001255214,"about_ca_system_score_gemma":0.00007783439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007510374,"about_ca_topic_score_gemma":0.0001979392,"domain_scores_codex":[0.9976307,0.000203523,0.0004274868,0.0004825291,0.0006695602,0.0005862243],"domain_scores_gemma":[0.9980931,0.0002542019,0.0001825173,0.0008900733,0.0001335927,0.0004465261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01647673,0.002587164,0.6713465,0.0008441545,0.001381793,0.001223684,0.001618723,0.000002233432,0.2935716,0.0001572027,0.002191397,0.008598711],"study_design_scores_gemma":[0.01309285,0.01025058,0.1658297,0.0002780028,0.000171023,0.00001906067,0.00003342946,0.00008776774,0.8096877,0.00007775189,0.0002379602,0.0002342424],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837587,0.00007053526,0.00002382118,0.00009442936,0.00007311555,0.001267013,0.00002058524,0.0001312486,0.01456056],"genre_scores_gemma":[0.9974356,0.00001200158,0.001137504,0.00008681409,0.00006136594,0.0001071361,0.0001070177,0.00007446121,0.0009780751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.516116,"threshold_uncertainty_score":0.9999654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03562589046420497,"score_gpt":0.2846581664059509,"score_spread":0.2490322759417459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}