{"id":"W2134857208","doi":"10.1086/444458","title":"Safety and Immunogenicity of 26-Valent Group A Streptococcus Vaccine in Healthy Adult Volunteers","year":2005,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Nova Scotia Health Authority; Dalhousie University","funders":"","keywords":"Immunogenicity; Medicine; Reactogenicity; Antibody; Antigen; Streptococcus pyogenes; Streptococcus; Immunology; Antibody titer; Pharyngitis; Antibody opsonization; Microbiology; Titer; Virology; Biology; Staphylococcus aureus; Internal medicine; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002034556,0.0002322855,0.0007385694,0.0001659744,0.00008626172,0.00001166429,0.00005352419,0.0001583676,0.0002239221],"category_scores_gemma":[0.000658322,0.0001954163,0.0003428413,0.0003163524,0.0001647191,0.0001080722,0.00007320887,0.000289618,0.00004164041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001808565,"about_ca_system_score_gemma":0.0001084653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005366587,"about_ca_topic_score_gemma":0.0009438439,"domain_scores_codex":[0.9977745,0.0001400168,0.00115157,0.0004611585,0.0001642496,0.0003085171],"domain_scores_gemma":[0.9984413,0.0004070908,0.0002069569,0.0003938767,0.0001589858,0.0003918278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001354904,0.004658911,0.9607844,0.00009459342,0.0002416623,0.000014935,0.00002273687,0.00002834866,0.00002022215,0.0002151845,0.0001654372,0.0323987],"study_design_scores_gemma":[0.01211376,0.002957447,0.9827701,0.0001609095,0.0003014395,0.00001390328,0.00003268327,0.0003711561,0.00003148478,0.0001407602,0.000954947,0.0001514282],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961544,0.001244947,0.00006487898,0.0004685556,0.0001918334,0.001069377,0.00006516661,0.0001502534,0.0005905516],"genre_scores_gemma":[0.9967793,0.00212689,0.00004660279,0.0006225666,0.0002113627,0.0001024833,0.00003419252,0.00002912875,0.00004743052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03224727,"threshold_uncertainty_score":0.7968848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186818273296727,"score_gpt":0.3523413652390281,"score_spread":0.3336595379093554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}