{"id":"W2134883341","doi":"10.1016/j.jnutbio.2010.07.015","title":"Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair","year":2010,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Montreal Children's Hospital; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"DNA repair; DNA glycosylase; Uracil-DNA glycosylase; Biochemistry; Uracil; Carcinogenesis; Methionine; Molecular biology; Enzyme; Biology; DNA damage; DNA; Chemistry; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001508943,0.0001129731,0.0002415494,0.0001551107,0.00003669773,0.0000148359,0.0001413359,0.0001054168,0.00003915039],"category_scores_gemma":[0.0007697085,0.00008599947,0.00006331241,0.0003607938,0.0001018478,0.00005899352,0.00005439273,0.0006378992,0.000001048782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001103873,"about_ca_system_score_gemma":0.0001860376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001830352,"about_ca_topic_score_gemma":0.00004771812,"domain_scores_codex":[0.9986041,0.00007187221,0.0004712461,0.0001641548,0.0004876925,0.000200901],"domain_scores_gemma":[0.9990228,0.0002221744,0.0001189666,0.0001737977,0.0003084907,0.0001537598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008780999,0.0005557369,0.01682491,0.00009046398,0.00002054779,0.00002124408,0.0001338831,0.000002553486,0.9811656,0.00001152165,0.0002261088,0.00006933155],"study_design_scores_gemma":[0.001798967,0.0002557511,0.3952498,0.0002614254,0.00005407195,0.0004109649,0.0001845605,0.0001111915,0.6011567,0.000271729,0.000139103,0.0001058077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950336,0.0005355465,0.000004299752,0.004101646,0.00004411545,0.0001695345,0.00001715234,0.000006844786,0.00008726347],"genre_scores_gemma":[0.9985906,0.0001068432,0.0008752989,0.0002076088,0.000146464,0.00000551391,0.000008840651,0.000008231258,0.0000505701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3800089,"threshold_uncertainty_score":0.3506956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687257530562005,"score_gpt":0.2863998973263827,"score_spread":0.2695273220207626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}