{"id":"W2134917687","doi":"10.2174/157489107780832622","title":"Recent Patents on Development of Nucleic Acid-based Antiviral Drugs against Seasonal and Pandemic Influenza Virus Infections","year":2007,"lang":"en","type":"review","venue":"Recent Patents on Anti-Infective Drug Discovery","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Neuraminidase; Oseltamivir; Pandemic; Virology; Influenza A virus subtype H5N1; Virus; Nucleic acid; Zanamivir; Influenza A virus; Biology; Medicine; Coronavirus disease 2019 (COVID-19); Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005721397,0.001079546,0.001513098,0.0005216551,0.000273083,0.0001148619,0.0003891012,0.0006370848,0.00002319697],"category_scores_gemma":[0.000141655,0.000917079,0.0006228659,0.0004723895,0.0002306258,0.00004353918,0.0003062928,0.0006642307,0.0001006921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003681086,"about_ca_system_score_gemma":0.0008445855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001626973,"about_ca_topic_score_gemma":0.00004215644,"domain_scores_codex":[0.9956753,0.0004262672,0.001187382,0.001346868,0.0006067127,0.0007574335],"domain_scores_gemma":[0.9978078,0.00009777491,0.0008813635,0.0006570763,0.0003338877,0.0002220713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002846108,0.001630879,0.007652113,0.001346851,0.0009076961,0.00001331238,0.00007225527,0.00003563416,0.004390566,0.000006828197,0.0003539092,0.9833053],"study_design_scores_gemma":[0.001973674,0.0008566538,0.004338566,0.008816805,0.0004211536,0.000005949916,0.00007601301,0.00001356236,0.0579903,0.000005477425,0.9239241,0.001577777],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6638145,0.3326914,0.00009522599,0.000006476048,0.000872748,0.001133406,0.0005455131,0.00003986232,0.0008008612],"genre_scores_gemma":[0.08544718,0.9119091,0.00002596984,0.0004982683,0.0001749966,0.0001000787,0.001635579,0.0001183406,0.00009047084],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.9817275,"threshold_uncertainty_score":0.999328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05228471400645406,"score_gpt":0.3335522670843761,"score_spread":0.2812675530779221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}