{"id":"W2134917687","doi":"10.2174/157489107780832622","title":"Recent Patents on Development of Nucleic Acid-based Antiviral Drugs against Seasonal and Pandemic Influenza Virus Infections","year":2007,"lang":"en","type":"review","venue":"Recent Patents on Anti-Infective Drug Discovery","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Neuraminidase; Oseltamivir; Pandemic; Virology; Influenza A virus subtype H5N1; Virus; Nucleic acid; Zanamivir; Influenza A virus; Biology; Medicine; Coronavirus disease 2019 (COVID-19); Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003593051,0.0009704803,0.001072169,0.001888334,0.0003349181,0.0007158898,0.0008423851,0.000841865,0.008165527],"category_scores_gemma":[0.0004150097,0.0002490444,0.0004861085,0.002293697,0.0003368756,0.001226368,0.000421207,0.001059356,0.004153513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006801579,"about_ca_system_score_gemma":0.0007633552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000659802,"about_ca_topic_score_gemma":0.001167117,"domain_scores_codex":[0.9998355,0.00001649295,0.00001388316,0.00002544232,0.00008535553,0.0000234183],"domain_scores_gemma":[0.9998741,0.00004565653,0.00002442618,0.000004399344,0.00003200687,0.00001935245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001193308,0.0001387146,0.0001230183,0.00986078,0.00006873032,0.0006932072,0.00008113894,0.0009105353,0.009887901,0.008624244,0.04841039,0.9210818],"study_design_scores_gemma":[0.0000313208,0.00014266,0.0003173341,0.0006534072,0.00004287841,0.00105626,0.00002304426,0.0001233796,0.00136458,0.001754654,0.9944794,0.00001116482],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001403302,0.9806405,0.0008652041,0.0007284974,0.0009367251,0.00004028541,0.0000853052,0.00004873136,0.01525133],"genre_scores_gemma":[0.003050594,0.9883053,0.0008810592,0.0004836755,0.0004339491,0.00003176746,0.000115523,0.000003520375,0.0066946],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008165527,"threshold_uncertainty_score":0.02731645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05228471400645406,"score_gpt":0.3335522670843761,"score_spread":0.2812675530779221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}