{"id":"W2134945394","doi":"10.1128/cvi.00529-09","title":"Updated Postlicensure Surveillance of the Meningococcal C Conjugate Vaccine in England and Wales: Effectiveness, Validation of Serological Correlates of Protection, and Modeling Predictions of the Duration of Herd Immunity","year":2010,"lang":"en","type":"article","venue":"Clinical and Vaccine Immunology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Herd immunity; Medicine; Carriage; Vaccination; Meningococcal vaccine; Incidence (geometry); Population; Serology; Conjugate vaccine; Herd; Confidence interval; Meningococcal disease; Vaccine efficacy; Immunology; Immunization; Neisseria meningitidis; Antibody; Environmental health; Internal medicine; Veterinary medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001048922,0.0001267882,0.0005910012,0.00006982394,0.00009585411,0.000002331846,0.0001174653,0.000397766,0.00002146124],"category_scores_gemma":[0.00077207,0.00007541972,0.00007499086,0.0002127684,0.0003430501,0.00006323788,0.0001782606,0.000515619,1.274629e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003131576,"about_ca_system_score_gemma":0.00003427444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008324654,"about_ca_topic_score_gemma":0.0004031753,"domain_scores_codex":[0.9977682,0.0009056802,0.001012255,0.0001861189,0.00001795806,0.0001098162],"domain_scores_gemma":[0.9982058,0.0005923544,0.0006087717,0.0002624604,0.0003208864,0.000009773986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009346363,0.0001497285,0.5120604,0.00004792021,0.000103156,1.766302e-8,0.00009840779,0.00004746999,0.4859999,0.0001258945,8.059652e-7,0.0004316982],"study_design_scores_gemma":[0.003352876,0.0006800933,0.9098139,0.00007318286,0.00006021453,0.00003886337,0.00004621533,0.0004369633,0.08509017,0.0003149242,0.00003572612,0.00005690343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981375,0.0005652292,0.00006217177,0.000198014,0.0005077262,0.0004727402,0.00004457299,0.000008211446,0.000003795197],"genre_scores_gemma":[0.9994743,0.0004522184,0.00001266301,0.000002520886,0.00001373324,0.00001232416,0.00002079181,0.000005852987,0.000005532323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4009097,"threshold_uncertainty_score":0.3075527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01997173495552353,"score_gpt":0.2753974583767715,"score_spread":0.255425723421248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}