{"id":"W2134945394","doi":"10.1128/cvi.00529-09","title":"Updated Postlicensure Surveillance of the Meningococcal C Conjugate Vaccine in England and Wales: Effectiveness, Validation of Serological Correlates of Protection, and Modeling Predictions of the Duration of Herd Immunity","year":2010,"lang":"en","type":"article","venue":"Clinical and Vaccine Immunology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Herd immunity; Medicine; Carriage; Vaccination; Meningococcal vaccine; Incidence (geometry); Population; Serology; Conjugate vaccine; Herd; Confidence interval; Meningococcal disease; Vaccine efficacy; Immunology; Immunization; Neisseria meningitidis; Antibody; Environmental health; Internal medicine; Veterinary medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003046187,0.0003781437,0.0005338315,0.0007844353,0.0001428536,0.0006197908,0.0005798894,0.0005248474,0.0003085778],"category_scores_gemma":[0.007163359,0.0003144506,0.0003461888,0.0005860801,0.0001774713,0.0006616559,0.000555874,0.0003503532,0.0001443398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001503753,"about_ca_system_score_gemma":0.0008319439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1687391,"about_ca_topic_score_gemma":0.1249693,"domain_scores_codex":[0.9987984,0.0005276874,0.0001343422,0.0002153283,0.000215653,0.00010864],"domain_scores_gemma":[0.9965253,0.0009678759,0.0009318949,0.0002432812,0.00119283,0.0001387248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000298075,0.00005938355,0.9713409,0.0001647647,0.0001505609,0.0002850294,0.0004967263,0.01025202,0.001945687,0.0001260249,0.000518739,0.014362],"study_design_scores_gemma":[0.00001419427,0.0002114383,0.9751041,0.0000434262,0.00005353079,0.0002036107,0.0001961849,0.02267704,0.0006385198,0.00006345563,0.0007787166,0.000015711],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968828,0.0004199286,0.001146065,0.00007577304,0.000004828336,0.00002716055,0.0009635488,0.00001215785,0.000467696],"genre_scores_gemma":[0.9977881,0.0001795395,0.0007371642,0.00003759363,0.000003446715,0.00002390636,0.00100672,0.000002700507,0.0002208969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1687391,"threshold_uncertainty_score":0.3355139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01997173495552353,"score_gpt":0.2753974583767715,"score_spread":0.255425723421248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}