{"id":"W2134957137","doi":"10.1038/nbt.2798","title":"Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape","year":2014,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":478,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Dental and Craniofacial Research; Common Fund; National Institute of Biomedical Imaging and Bioengineering; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; Harvard Stem Cell Institute; National Institutes of Health; National Human Genome Research Institute; Massachusetts Institute of Technology","keywords":"Chromatin; Chromatin immunoprecipitation; Transcription factor; Biology; Computational biology; Population; Binding site; Genome; DNase I hypersensitive site; Genetics; Deoxyribonuclease I; Gene; Promoter; Gene expression; Base sequence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002807850877465943,"score_gpt":0.1942205810885083,"score_spread":0.1914127302110423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}