{"id":"W2134985318","doi":"10.1136/bmj.e3799","title":"Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial","year":2012,"lang":"en","type":"article","venue":"BMJ","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Research for Patient Benefit Programme; Dr. Falk Pharma; Tommy's; Nottingham University Hospitals NHS Trust; Imperial College London; University of Nottingham; Imperial College Healthcare NHS Trust; National Institute for Health and Care Research","keywords":"Ursodeoxycholic acid; Medicine; Cholestasis of pregnancy; Pregnancy; Placebo; Gestation; Caesarean section; Cholestasis; Obstetrics; Itching; Randomized controlled trial; Bile acid; Fetal distress; Internal medicine; Fetus; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007167831,0.0002219387,0.0006898436,0.0001468085,0.00003136112,0.00001281736,0.0001044263,0.0001567979,0.00005065152],"category_scores_gemma":[0.00007477509,0.0001674306,0.00009788408,0.0001804722,0.00012289,0.0001446884,0.00002632234,0.0002283642,0.000004763117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009203874,"about_ca_system_score_gemma":0.00007394441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001498317,"about_ca_topic_score_gemma":0.00002515224,"domain_scores_codex":[0.9980417,0.0001073672,0.0007075872,0.0002969144,0.0003815857,0.0004648244],"domain_scores_gemma":[0.9989405,0.0001940221,0.0002274755,0.0003458173,0.00003391712,0.0002583114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9658334,0.0005852622,0.009277779,0.0001803619,0.000548791,0.00009450877,0.002405354,3.124891e-7,0.0004669135,0.00005897076,0.0000508958,0.02049749],"study_design_scores_gemma":[0.9096203,0.003255462,0.08281845,0.0007823114,0.0005820592,0.000003337014,0.001224339,0.000004111393,0.001119648,0.00001196489,0.0002911911,0.0002868469],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992556,0.0004705524,0.00004869319,0.0000493359,0.002181558,0.002577311,0.000006641984,0.00003391342,0.002076038],"genre_scores_gemma":[0.9976518,0.0004470116,0.0007928828,0.00001460628,0.0006785977,0.0002669886,0.000007251887,0.00003089515,0.0001099426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07354067,"threshold_uncertainty_score":0.682762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04767550525230533,"score_gpt":0.3345377057536867,"score_spread":0.2868622005013814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}