{"id":"W2134985318","doi":"10.1136/bmj.e3799","title":"Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial","year":2012,"lang":"en","type":"article","venue":"BMJ","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Research for Patient Benefit Programme; Dr. Falk Pharma; Tommy's; Nottingham University Hospitals NHS Trust; Imperial College London; University of Nottingham; Imperial College Healthcare NHS Trust; National Institute for Health and Care Research","keywords":"Ursodeoxycholic acid; Medicine; Cholestasis of pregnancy; Pregnancy; Placebo; Gestation; Caesarean section; Cholestasis; Obstetrics; Itching; Randomized controlled trial; Bile acid; Fetal distress; Internal medicine; Fetus; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004038906,0.00165734,0.003672073,0.0005701467,0.0005679482,0.001147093,0.001061556,0.002744857,0.007228814],"category_scores_gemma":[0.006307045,0.0008971475,0.002232413,0.0005328016,0.001528628,0.001032413,0.000704593,0.00153565,0.0007557879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001192319,"about_ca_system_score_gemma":0.00181046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454693,"about_ca_topic_score_gemma":0.002458425,"domain_scores_codex":[0.9969698,0.002154187,0.0002171742,0.0002796641,0.0001748315,0.0002044209],"domain_scores_gemma":[0.9961563,0.001662616,0.0009671143,0.0003069615,0.0002341044,0.0006730299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9913934,0.003054616,0.0001764049,0.0004297837,0.0002679842,0.00001400045,0.00002351386,0.00007878008,0.0005979023,0.00003317371,0.00008983746,0.003840542],"study_design_scores_gemma":[0.9114172,0.08704793,0.0007677345,0.00003866971,0.0001710691,0.00001329028,0.00001399627,0.0001807713,0.0001125184,0.00007946799,0.0001491809,0.000008069253],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801624,0.005367405,0.00103796,0.0007531013,0.000799527,0.01004336,0.0006781698,0.00008130946,0.001076775],"genre_scores_gemma":[0.9767669,0.002638942,0.002817612,0.0007730771,0.0006831281,0.0131633,0.000421569,0.00001097477,0.002724468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007228814,"threshold_uncertainty_score":0.0241828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04767550525230533,"score_gpt":0.3345377057536867,"score_spread":0.2868622005013814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}