{"id":"W2135041781","doi":"10.1016/s0022-2143(03)00148-3","title":"Apoptosis and oxidants in the heart","year":2003,"lang":"en","type":"review","venue":"Journal of Laboratory and Clinical Medicine","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":235,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Apoptosis; TUNEL assay; Oxidative stress; Reactive oxygen species; Biology; Mitochondrion; Programmed cell death; Cell biology; Caspase; Intrinsic apoptosis; Terminal deoxynucleotidyl transferase; Myocyte; Cancer research; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002291999,0.0001371003,0.0007506663,0.00005096821,0.00002973743,0.000008404713,0.00009216795,0.0002978225,0.000006842291],"category_scores_gemma":[0.0003172827,0.00006697489,0.0001076474,0.0001131595,0.0001385913,0.000002785094,0.00002008721,0.0003413827,3.800403e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003927656,"about_ca_system_score_gemma":0.00009088596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.968227e-7,"about_ca_topic_score_gemma":0.000001093022,"domain_scores_codex":[0.9983605,0.0004716293,0.0008038383,0.0001460025,0.0001306704,0.00008738166],"domain_scores_gemma":[0.9991401,0.000152517,0.0004067703,0.0001371203,0.00007798898,0.00008546699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000051384,0.0001543457,0.0003889809,0.001614708,0.0001943879,0.00002630138,0.00003864009,1.089739e-7,0.0005491251,0.0001596989,0.004762253,0.9920601],"study_design_scores_gemma":[0.0004860682,0.0007860727,0.0002793766,0.001853987,0.0003201561,0.0001243464,0.00005457973,1.780012e-7,0.00001139927,0.00004552698,0.9959608,0.00007750194],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00821999,0.9910395,0.00001529921,0.0002086585,0.0003570847,0.0001163752,0.000003084986,4.68613e-7,0.00003950581],"genre_scores_gemma":[0.001265616,0.9973632,0.00007966496,0.0005372809,0.0007050351,0.000001638978,0.000004772464,0.000009280881,0.00003353135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919826,"threshold_uncertainty_score":0.2731157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04774439057293028,"score_gpt":0.4005803421778319,"score_spread":0.3528359516049016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}