{"id":"W2135102498","doi":"10.1093/genetics/165.3.997","title":"Phenotypic and Transcriptional Plasticity Directed by a Yeast Mitogen-Activated Protein Kinase Network","year":2003,"lang":"en","type":"article","venue":"Genetics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Ontario Institute for Cancer Research; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Phenotype; Genetics; Protein kinase A; Yeast; Mitogen-activated protein kinase; Saccharomyces cerevisiae; Kinase; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008640294,0.0001502221,0.0001060208,0.0001307363,0.0001081261,0.0002558932,0.0001424681,0.0001111991,0.0005500409],"category_scores_gemma":[0.0002150353,0.0001068941,0.0001453737,0.00007921219,0.0001916623,0.0001876881,0.000326167,0.000199925,0.0001296988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956353,"about_ca_system_score_gemma":0.0001075133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002306932,"about_ca_topic_score_gemma":0.0004207474,"domain_scores_codex":[0.9999193,0.00001156396,0.000003545714,0.00002046018,0.00002010674,0.00002493828],"domain_scores_gemma":[0.9999201,0.00001643302,0.00001614288,0.00001409057,0.0000105026,0.00002280607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001207925,0.00001368144,0.0009668549,0.00001191345,0.00000356274,0.00006174845,0.00002165153,0.001168739,0.9947784,0.0004661698,0.00003398905,0.002352535],"study_design_scores_gemma":[0.00005534017,0.000355377,0.05337125,0.00001574991,0.00003455709,0.0008455241,0.0002108849,0.04637318,0.8926748,0.002608239,0.003426081,0.00002895902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974036,0.00007432146,0.001464457,0.00003100171,0.000002975564,0.000003825246,0.00005278057,0.00004716916,0.0009198137],"genre_scores_gemma":[0.9991127,0.00005117714,0.0004036824,0.000009908151,0.000001232292,0.000005498332,0.00008774214,0.000006361325,0.0003217697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005500409,"threshold_uncertainty_score":0.002144992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01093601187223663,"score_gpt":0.2295984206908678,"score_spread":0.2186624088186311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}