{"id":"W2135122661","doi":"10.1128/mcb.00004-10","title":"Doubles Game: Src-Stat3 versus p53-PTEN in Cellular Migration and Invasion","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Podosome; Invadopodia; PTEN; Proto-oncogene tyrosine-protein kinase Src; Biology; Cell biology; Effector; Cancer research; Cell migration; Signal transduction; Cell; Cancer cell; PI3K/AKT/mTOR pathway; Cytoskeleton; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002109989,0.0003361531,0.0003436771,0.0003907121,0.0001701319,0.0004294309,0.0001788391,0.0003156333,0.003658501],"category_scores_gemma":[0.0001251012,0.0001375885,0.0002260062,0.000183372,0.0003632369,0.0003298073,0.0002624041,0.0007170396,0.0005836775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002938742,"about_ca_system_score_gemma":0.0003473928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004011231,"about_ca_topic_score_gemma":0.0006779156,"domain_scores_codex":[0.9997442,0.00003099337,0.00002637648,0.0000408679,0.00008644723,0.00007115038],"domain_scores_gemma":[0.9998628,0.0000226982,0.00002787693,0.00001172783,0.000009703462,0.00006517812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004248752,0.00006010361,0.000200241,0.00004412822,0.000009711551,0.0001163215,0.000006790367,0.00009556953,0.9959682,0.0006091936,0.0001246166,0.002340144],"study_design_scores_gemma":[0.0001153036,0.0005106392,0.002506644,0.000005620246,0.00003228217,0.000713898,0.00003623595,0.002202239,0.9910115,0.000256221,0.002604192,0.00000526349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918646,0.00188345,0.001932126,0.0003497425,0.0001258937,0.00003010924,0.0002283224,0.0001075815,0.003478015],"genre_scores_gemma":[0.9962987,0.0004027088,0.0006718691,0.00008268093,0.00001579621,0.00002170985,0.0001746878,0.00001186156,0.002319899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003658501,"threshold_uncertainty_score":0.01223892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009140064318172684,"score_gpt":0.2426394833375705,"score_spread":0.2334994190193978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}