{"id":"W2135122661","doi":"10.1128/mcb.00004-10","title":"Doubles Game: Src-Stat3 versus p53-PTEN in Cellular Migration and Invasion","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Podosome; Invadopodia; PTEN; Proto-oncogene tyrosine-protein kinase Src; Biology; Cell biology; Effector; Cancer research; Cell migration; Signal transduction; Cell; Cancer cell; PI3K/AKT/mTOR pathway; Cytoskeleton; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003062788,0.0002653301,0.0002433466,0.0001066648,0.00006849393,0.00003798771,0.0001790662,0.0004921717,0.00003044237],"category_scores_gemma":[0.00008823886,0.00025849,0.00007289989,0.0001089667,0.000270219,0.000007235968,0.0001760751,0.0002796655,0.000006323891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197965,"about_ca_system_score_gemma":0.00006400771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001925094,"about_ca_topic_score_gemma":0.0005783985,"domain_scores_codex":[0.9984545,0.0001305288,0.0002771196,0.0006714931,0.00009458519,0.0003717997],"domain_scores_gemma":[0.9992905,0.00002629823,0.00009125368,0.0004032138,0.00005870004,0.000130029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002307439,0.00003858978,0.005397976,0.00002215196,0.00003715669,0.00003016185,0.00006166991,0.00001308014,0.99054,0.0006780568,0.0000672689,0.002883103],"study_design_scores_gemma":[0.001856486,0.0004505143,0.0004369919,0.00001245838,0.00003163298,0.00001675107,0.0000487683,0.0002000554,0.9702891,0.0005359595,0.02578043,0.0003408431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902011,0.005169909,0.003246505,0.0002395613,0.0004992462,0.0002254296,0.00001549128,0.00001750101,0.0003853043],"genre_scores_gemma":[0.9981017,0.0003799338,0.0006297046,0.0002123328,0.0001646449,0.00003333135,0.0003611686,0.0000342603,0.00008291718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02571316,"threshold_uncertainty_score":0.9999867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009140064318172684,"score_gpt":0.2426394833375705,"score_spread":0.2334994190193978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}