{"id":"W2135148404","doi":"10.1124/dmd.114.056929","title":"Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters","year":2014,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Washington","keywords":"Multidrug resistance-associated protein 2; Transporter; Organic anion transporter 1; Efflux; Gene expression; Biology; Fetus; Internal medicine; Endocrinology; Organic anion-transporting polypeptide; Pharmacology; Gene; Medicine; ATP-binding cassette transporter; Biochemistry; Genetics; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375316,0.0001530798,0.0003369433,0.00009956911,0.0001113278,0.00001254072,0.00003644435,0.00004842398,0.00002714958],"category_scores_gemma":[0.000003904272,0.0001210244,0.00006576678,0.00005754711,0.0000770062,0.0001035547,0.000009063324,0.00008973842,9.387775e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000517747,"about_ca_system_score_gemma":0.000006104343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004296616,"about_ca_topic_score_gemma":0.00001975741,"domain_scores_codex":[0.9991292,0.00002997006,0.0002711809,0.0002349964,0.0001750101,0.0001596519],"domain_scores_gemma":[0.9995918,0.00001002889,0.0000813956,0.0001508259,0.00003451516,0.0001313992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001459683,0.0001381893,0.007834681,0.0003933526,0.00002049073,0.00002436681,0.001870318,9.740332e-7,0.9881991,0.0004767462,0.00001408274,0.0008816996],"study_design_scores_gemma":[0.001539737,0.00003614139,0.6624926,0.0003374299,0.0002392189,0.00002454372,0.0001074346,0.00001379148,0.3346598,0.0003760041,0.00005791719,0.0001153439],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968577,0.0006052554,0.001849714,0.000168217,0.00008860924,0.0002077337,0.00001331024,0.00003436916,0.0001750744],"genre_scores_gemma":[0.997673,0.0001038567,0.001616691,0.0001942376,0.0001301253,0.00001171538,0.0001318181,0.00001912961,0.0001193982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.654658,"threshold_uncertainty_score":0.4935233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004549969919058464,"score_gpt":0.210277215225629,"score_spread":0.2057272453065705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}