{"id":"W2135289089","doi":"10.1128/mcb.01142-12","title":"Luman/CREB3 Recruitment Factor Regulates Glucocorticoid Receptor Activity and Is Essential for Prolactin-Mediated Maternal Instinct","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internal medicine; Biology; Endocrinology; Glucocorticoid receptor; Prolactin; Glucocorticoid; Endoplasmic reticulum; Receptor; Psychological repression; Unfolded protein response; Corticotropin-releasing hormone; Repressor; Hypothalamus; Cell biology; Hormone; Gene; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002119152,0.0002242833,0.0003936612,0.00008388005,0.0001116457,0.00001716035,0.00004754019,0.000253576,0.0001389657],"category_scores_gemma":[0.0000416872,0.0001837974,0.00007042164,0.00006124315,0.0001070817,0.00005415404,0.00006537961,0.0001658719,0.00001632896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004828103,"about_ca_system_score_gemma":0.00009680039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005017361,"about_ca_topic_score_gemma":0.000004559599,"domain_scores_codex":[0.9986824,0.00008331869,0.0002504293,0.0003747386,0.00009887673,0.0005102014],"domain_scores_gemma":[0.9993095,0.00003782815,0.0001291911,0.0001841281,0.00005645312,0.0002828497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005901515,0.0001263178,0.07930833,0.0002875528,0.0001319751,0.000005365147,0.0003419369,1.527533e-8,0.9114249,0.0008109002,0.00006465102,0.006907929],"study_design_scores_gemma":[0.002354166,0.0006237265,0.08788319,0.00004212602,0.00009320703,0.00005295587,0.0000418975,0.00006492997,0.8967003,0.0003247439,0.01156287,0.0002559275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939232,0.001575035,0.001824016,0.0006399943,0.0003633662,0.001449666,0.00004370118,0.00003984975,0.0001412049],"genre_scores_gemma":[0.995728,0.001900214,0.001158138,0.0006620972,0.0001528128,0.0001110925,0.0001596772,0.00002995971,0.00009798667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01472461,"threshold_uncertainty_score":0.7495041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03047570983934452,"score_gpt":0.2987496336697642,"score_spread":0.2682739238304197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}