{"id":"W2135289089","doi":"10.1128/mcb.01142-12","title":"Luman/CREB3 Recruitment Factor Regulates Glucocorticoid Receptor Activity and Is Essential for Prolactin-Mediated Maternal Instinct","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internal medicine; Biology; Endocrinology; Glucocorticoid receptor; Prolactin; Glucocorticoid; Endoplasmic reticulum; Receptor; Psychological repression; Unfolded protein response; Corticotropin-releasing hormone; Repressor; Hypothalamus; Cell biology; Hormone; Gene; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008281576,0.0003261415,0.0001999027,0.000224879,0.0002339035,0.0002079321,0.0002855062,0.0002230314,0.002184117],"category_scores_gemma":[0.000153317,0.000125646,0.0002118837,0.00007264483,0.0003057495,0.0001288027,0.0002672483,0.0004329518,0.0008852244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004225188,"about_ca_system_score_gemma":0.0003574752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086328,"about_ca_topic_score_gemma":0.001760761,"domain_scores_codex":[0.9999063,0.00001167306,0.00000470651,0.00002187213,0.00002220551,0.00003334236],"domain_scores_gemma":[0.9998585,0.0000106482,0.00004122331,0.00001180135,0.00001146782,0.00006632943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001547575,0.00001301655,0.0002967443,0.00002278716,0.000001859429,0.0001229482,0.000006836019,0.00001860826,0.9976547,0.00009016152,0.00009297832,0.001524599],"study_design_scores_gemma":[0.00005496409,0.0002002911,0.04203182,0.00001979041,0.00001665392,0.00127718,0.00005557981,0.001769611,0.9481046,0.0001851396,0.006266821,0.0000176771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874601,0.002728164,0.004780947,0.0002579716,0.00006799754,0.00002409344,0.00115131,0.00045545,0.003074037],"genre_scores_gemma":[0.9929441,0.0004494791,0.002091449,0.00008960497,0.00001298405,0.00003112706,0.0009993335,0.00006739914,0.003314418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002184117,"threshold_uncertainty_score":0.007306635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03047570983934452,"score_gpt":0.2987496336697642,"score_spread":0.2682739238304197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}