{"id":"W2135293060","doi":"10.1517/14712590903110709","title":"Nimotuzumab: a novel anti-EGFR monoclonal antibody that retains anti-EGFR activity while minimizing skin toxicity","year":2009,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McGill University","funders":"","keywords":"Nimotuzumab; Medicine; Monoclonal antibody; Clinical trial; Pharmacology; Epidermal growth factor receptor; Drug; Toxicity; EGFR inhibitors; Oncology; Cancer research; Cancer; Antibody; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004666156,0.0006392383,0.001288938,0.001497616,0.0001842727,0.0006569354,0.0008947925,0.0008412544,0.002502155],"category_scores_gemma":[0.0002671882,0.0001597362,0.0003268331,0.001267864,0.0002783737,0.0006816627,0.0003541246,0.0007839971,0.002668864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006638049,"about_ca_system_score_gemma":0.0006747317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000730082,"about_ca_topic_score_gemma":0.001807312,"domain_scores_codex":[0.9998109,0.00003026566,0.00001696251,0.00002942268,0.0000927094,0.00001978667],"domain_scores_gemma":[0.9999288,0.00001750566,0.00001834752,0.000002489431,0.00001969158,0.00001311356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009957382,0.0001061408,0.0001488833,0.00740707,0.00007496518,0.0004382771,0.00002739228,0.0002952972,0.01025471,0.00218651,0.01826905,0.9606922],"study_design_scores_gemma":[0.00005851036,0.0001410586,0.0005580567,0.0007325849,0.00006227048,0.002257249,0.00002102893,0.0001098277,0.003351067,0.0007721214,0.9919226,0.00001366792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005541595,0.9953453,0.000601471,0.0004109844,0.0001909544,0.00001831559,0.00002885071,0.0000186849,0.002831376],"genre_scores_gemma":[0.002924008,0.9926788,0.0009208638,0.0003749689,0.0001768195,0.00002403119,0.0001079415,0.000002953627,0.002789641],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002502155,"threshold_uncertainty_score":0.008370519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2533466771946822,"score_gpt":0.4340411261167223,"score_spread":0.1806944489220401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}