{"id":"W2135416777","doi":"10.1093/toxsci/kfs001","title":"DNA Double-Strand Breaks and DNA Recombination in Benzene Metabolite-Induced Genotoxicity","year":2012,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"DNA damage; Genotoxicity; Molecular biology; DNA; Carcinogen; Chemistry; Reactive oxygen species; DNA repair; Oxidative stress; Biology; Toxicity; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001021663,0.000150923,0.0001893575,0.00006249158,0.000180111,0.00005759864,0.00019065,0.0001935434,0.00006582648],"category_scores_gemma":[0.00004832961,0.0001144184,0.00005482946,0.0002370033,0.0001912948,0.00002079792,0.0001498309,0.00009830656,0.000004395074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002553482,"about_ca_system_score_gemma":0.00004208297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005118511,"about_ca_topic_score_gemma":0.0001595705,"domain_scores_codex":[0.9986116,0.00009935538,0.0002195618,0.0003929343,0.000210531,0.0004659977],"domain_scores_gemma":[0.9995772,0.00002764576,0.00006754296,0.0001302337,0.00002759827,0.0001697272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000479431,0.0002237779,0.01987408,0.000004525138,0.000007097506,0.000001144535,0.00006084054,0.00000998105,0.9747671,0.001271119,0.00002146301,0.00371086],"study_design_scores_gemma":[0.0007620052,0.000485687,0.3521294,0.000003195869,0.000009783189,0.00001585062,0.000115804,0.00004115478,0.6444365,0.0003365228,0.001463857,0.0002002577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957915,0.0006306889,0.00006665403,0.0003632153,0.0001520249,0.0002904274,0.000007593177,0.00001192581,0.002685952],"genre_scores_gemma":[0.9989031,0.0001172272,0.0004219913,0.0003172263,0.0001310814,0.00003249345,0.00001165478,0.000004640412,0.00006059964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3322553,"threshold_uncertainty_score":0.4665849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04966756957196707,"score_gpt":0.3189499449608867,"score_spread":0.2692823753889197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}