{"id":"W2135416777","doi":"10.1093/toxsci/kfs001","title":"DNA Double-Strand Breaks and DNA Recombination in Benzene Metabolite-Induced Genotoxicity","year":2012,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"DNA damage; Genotoxicity; Molecular biology; DNA; Carcinogen; Chemistry; Reactive oxygen species; DNA repair; Oxidative stress; Biology; Toxicity; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003453607,0.0005059844,0.0002773921,0.0004202935,0.0001772342,0.0002104953,0.0002304024,0.0005844161,0.001796962],"category_scores_gemma":[0.0002357637,0.0002787391,0.000389955,0.0002213119,0.0001852561,0.0002085537,0.0002468626,0.0005051089,0.0003648715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000187368,"about_ca_system_score_gemma":0.0001655966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000503112,"about_ca_topic_score_gemma":0.0004740827,"domain_scores_codex":[0.9996731,0.0001084852,0.00002133369,0.00004480862,0.0001079339,0.00004425361],"domain_scores_gemma":[0.9997899,0.0000234988,0.0001017213,0.00002030491,0.00003878138,0.00002594651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001379428,0.00003003007,0.0006780499,0.00008539358,0.00001029186,0.00008634794,0.00001987164,0.00005445886,0.9972751,0.0000474188,0.00001799197,0.001557155],"study_design_scores_gemma":[0.00002178017,0.001503181,0.03915672,0.00002371043,0.00005504565,0.001981436,0.00006387369,0.0006980919,0.9536597,0.0001173754,0.002707421,0.00001175161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620318,0.02347978,0.01189166,0.0001483913,0.00004164312,0.0000835759,0.0003095966,0.00009647272,0.001917041],"genre_scores_gemma":[0.9912293,0.004738661,0.002115778,0.00003624073,0.00001206427,0.00003889973,0.00037158,0.000007464482,0.001449967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001796962,"threshold_uncertainty_score":0.006011426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04966756957196707,"score_gpt":0.3189499449608867,"score_spread":0.2692823753889197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}